{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Akhtar M"],"funding":["FIC NIH HHS","National Institutes of Health","Wellcome Trust","NIH HHS"],"pagination":["e0265425"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12802145"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(1)"],"pubmed_abstract":["Bacteriophages (phages) likely play a critical role in modulating transmission dynamics of diarrheal pathogens. This study investigated the role of phages in modulating the prevalence and seasonal patterns of major diarrheal pathogens, <i>Vibrio cholerae</i> O1 (VCO1), enterotoxigenic <i>Escherichia coli</i> (ETEC), <i>Shigella</i> spp., and <i>Salmonella</i> spp. in diarrheal patients and environmental wastewater specimens collected from six different sites in Dhaka, Bangladesh, in 2024. VCO1, ETEC, <i>Shigella</i>, and <i>Salmonella</i> were detected in 10.1%, 7.8%, 1.7%, and 2.4% of diarrheal specimens, respectively. In contrast, phages targeting these pathogens were more frequently isolated, with detection rates of 20% for VCO1, 30% for ETEC, 57% for <i>Shigella</i>, and 9.2% for <i>Sa"],"journal":["mBio"],"pubmed_title":["Clinical and environmental wastewater-based bacteriophage surveillance for high-impact diarrheal diseases, including cholera, in Bangladesh."],"pmcid":["PMC12802145"],"funding_grant_id":["No 206194","D43 TW005572","206194"],"pubmed_authors":["Hussain SN","Begum YA","Qadri F","Firoj MG","Bhuiyan TR","Chowdhury F","Shapiro BJ","Khan AI","Islam Bhuiyan MA","Amin MA","Islam MT","Rahman MM","Jubair M","Afroz R","Nelson EJ","Ryan ET","Akhtar M","Parvin N","Nafsi NN","Khanam F","Thomson NR"],"additional_accession":[]},"is_claimable":false,"name":"Clinical and environmental wastewater-based bacteriophage surveillance for high-impact diarrheal diseases, including cholera, in Bangladesh.","description":"Bacteriophages (phages) likely play a critical role in modulating transmission dynamics of diarrheal pathogens. This study investigated the role of phages in modulating the prevalence and seasonal patterns of major diarrheal pathogens, <i>Vibrio cholerae</i> O1 (VCO1), enterotoxigenic <i>Escherichia coli</i> (ETEC), <i>Shigella</i> spp., and <i>Salmonella</i> spp. in diarrheal patients and environmental wastewater specimens collected from six different sites in Dhaka, Bangladesh, in 2024. VCO1, ETEC, <i>Shigella</i>, and <i>Salmonella</i> were detected in 10.1%, 7.8%, 1.7%, and 2.4% of diarrheal specimens, respectively. In contrast, phages targeting these pathogens were more frequently isolated, with detection rates of 20% for VCO1, 30% for ETEC, 57% for <i>Shigella</i>, and 9.2% for <i>Sa","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-11T05:19:08.388Z","creation":"2026-06-11T03:07:43.602Z"},"accession":"S-EPMC12802145","cross_references":{"pubmed":["41363802"],"doi":["10.1128/mbio.02654-25"]}}