{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Maier A"],"funding":["Boris Canessa ALS Stiftung","Martin Herrenknecht Fonds for ALS Research"],"pagination":["250-259"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12803583"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["73(2)"],"pubmed_abstract":["<h4>Introduction/aims</h4>The harmonized version of the ALS Functional Rating Scale - Revised (ALSFRS-R) is typically administered according to standard operating procedures (SOPs) to ensure procedural consistency. In contrast, obtaining the self-explanatory (SE) version of the ALSFRS-R does not include the use of SOPs. The aim of this study was to examine the level of agreement between the harmonized and the SE version of the ALSFRS-R in a cohort of ALS patients.<h4>Methods</h4>In a prospective study, the harmonized ALSFRS-R was assessed in 107 ALS patients. In parallel, all patients independently completed the ALSFRS-R-SE, either on a printed form (n = 36) or remotely via the ALS App (n = 71). Agreement between methods was investigated using Spearman's correlation, Lin's concordance corr"],"journal":["Muscle & nerve"],"pubmed_title":["Agreement Between the Harmonized and the Self-Explanatory Versions of the Revised ALS Functional Rating Scale in a Clinical Setting."],"pmcid":["PMC12803583"],"funding_grant_id":["H4017703513237604"],"pubmed_authors":["Riitano A","Spittel S","Meyer T","Kettemann D","Koc Y","Kolzarek F","Munch C","Maier A","Norden J","Schmitt P","Steinfurth L","Subramanian S"],"additional_accession":[]},"is_claimable":false,"name":"Agreement Between the Harmonized and the Self-Explanatory Versions of the Revised ALS Functional Rating Scale in a Clinical Setting.","description":"<h4>Introduction/aims</h4>The harmonized version of the ALS Functional Rating Scale - Revised (ALSFRS-R) is typically administered according to standard operating procedures (SOPs) to ensure procedural consistency. In contrast, obtaining the self-explanatory (SE) version of the ALSFRS-R does not include the use of SOPs. The aim of this study was to examine the level of agreement between the harmonized and the SE version of the ALSFRS-R in a cohort of ALS patients.<h4>Methods</h4>In a prospective study, the harmonized ALSFRS-R was assessed in 107 ALS patients. In parallel, all patients independently completed the ALSFRS-R-SE, either on a printed form (n = 36) or remotely via the ALS App (n = 71). Agreement between methods was investigated using Spearman's correlation, Lin's concordance corr","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-06-06T13:18:09.176Z","creation":"2026-05-31T03:07:22.079Z"},"accession":"S-EPMC12803583","cross_references":{"pubmed":["41328555"],"doi":["10.1002/mus.70092"]}}