{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhou H"],"funding":["Key Technologies Research and Development Program","Xihua University"],"pagination":["103428"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12807793"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["33"],"pubmed_abstract":["Organophosphate esters (OPEs), as commonly used flame retardant and plasticizer, emerging organic pollutants, exhibit concerning contamination levels, particularly in widely consumed rice-based foods. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for simultaneous determination of 5 OPEs in rice-based products. According to recoveries and matrix effects as indicators, quality and proportion of different purification fillers were mainly optimized to fabricate a purification cartridge, simplifying and reducing the pre-treatment process and cost. The proposed method showed excellent linearity (0.08-500 μg kg<sup>-1</sup>, with all correlation coefficients exceeding 0.99), with improved method detection and quantification limit (MDL and MQL): 0.0047-0.1309 and"],"journal":["Food chemistry: X"],"pubmed_title":["Development and validation of the LC-MS/MS method based on self-made purification column for simultaneous determination of novel organophosphate esters in rice-based products."],"pmcid":["PMC12807793"],"funding_grant_id":["2023YFF1104800"],"pubmed_authors":["Yang X","Li Z","Huang Y","Cao J","Qiao D","Gu M","Xiao F","Chen X","Shao B","Zhou H"],"additional_accession":[]},"is_claimable":false,"name":"Development and validation of the LC-MS/MS method based on self-made purification column for simultaneous determination of novel organophosphate esters in rice-based products.","description":"Organophosphate esters (OPEs), as commonly used flame retardant and plasticizer, emerging organic pollutants, exhibit concerning contamination levels, particularly in widely consumed rice-based foods. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for simultaneous determination of 5 OPEs in rice-based products. According to recoveries and matrix effects as indicators, quality and proportion of different purification fillers were mainly optimized to fabricate a purification cartridge, simplifying and reducing the pre-treatment process and cost. The proposed method showed excellent linearity (0.08-500 μg kg<sup>-1</sup>, with all correlation coefficients exceeding 0.99), with improved method detection and quantification limit (MDL and MQL): 0.0047-0.1309 and","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-10T05:26:00.002Z","creation":"2026-06-10T03:07:15.459Z"},"accession":"S-EPMC12807793","cross_references":{"pubmed":["41551784"],"doi":["10.1016/j.fochx.2025.103428"]}}