{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Denysenko-Bennett M"],"funding":["Institute of Botany, Faculty of Biology, Jagiellonian University, Kraków, Poland","NSERC of Canada Discovery"],"pagination":["2056"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12808232"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(1)"],"pubmed_abstract":["Horizontal Gene Transfer (HGT) is a phenomenon of DNA transfer between organisms that does not involve a parent-offspring relationship. HGT is believed to play an important role in all groups of organisms, including plants, and especially in parasites. Here we describe a chain of transfers from Cuscuta (Convolvulaceae) to Orobanche rigens (Orobanchaceae)-both parasitic plants-via a host belonging to tribe Genisteae (Fabaceae). During its \"journey\" between genomes, the transferred sequence, which we named Pytheas, was altered by deletions, additions of new segments from the current genome, substitutions, and rearrangements. This is the first robustly documented case of a multi-step transfer pathway-involving one IGT and two HGTs-connecting three plant species. Specifically, this system invo"],"journal":["Scientific reports"],"pubmed_title":["Horizontal gene transfer of the Pytheas sequence from Cuscuta to Orobanche via a host-mediated pathway."],"pmcid":["PMC12808232"],"funding_grant_id":["326439","K/DSC/003923"],"pubmed_authors":["Szklarczyk M","Joachimiak AJ","Stefanovic S","Denysenko-Bennett M","Kwolek D","Goralski G","Piwowarczyk R","Schneider AC"],"additional_accession":[]},"is_claimable":false,"name":"Horizontal gene transfer of the Pytheas sequence from Cuscuta to Orobanche via a host-mediated pathway.","description":"Horizontal Gene Transfer (HGT) is a phenomenon of DNA transfer between organisms that does not involve a parent-offspring relationship. HGT is believed to play an important role in all groups of organisms, including plants, and especially in parasites. Here we describe a chain of transfers from Cuscuta (Convolvulaceae) to Orobanche rigens (Orobanchaceae)-both parasitic plants-via a host belonging to tribe Genisteae (Fabaceae). During its \"journey\" between genomes, the transferred sequence, which we named Pytheas, was altered by deletions, additions of new segments from the current genome, substitutions, and rearrangements. This is the first robustly documented case of a multi-step transfer pathway-involving one IGT and two HGTs-connecting three plant species. Specifically, this system invo","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-06T17:14:21.49Z","creation":"2026-06-03T03:09:53.387Z"},"accession":"S-EPMC12808232","cross_references":{"pubmed":["41381821"],"doi":["10.1038/s41598-025-31853-x"]}}