{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["33"],"submitter":["Yin L"],"pubmed_abstract":["To meet the increasing demand for green and sustainable delivery systems in food, cosmetics, and pharmaceuticals and address the research gap in natural polyphenol-cellulose nanocrystal (CNC) composite stabilizers, this study developed a bio-based Pickering emulsion stabilizer via hydrogen bonding between 6'-<i>O</i>-caffeoylarbutin (CA) and CNCs. Results demonstrated CA/CNCs self-assembled into a dense interfacial layer, endowing the emulsion with exceptional stability that was reflected in over 85% curcumin enscapsulation efficiency after 30 days of dark storage and structural integrity at up to 80 °C, while CA-curcumin synergism enhanced antioxidant activity with 76.9% DPPH and 81.2% ABTS<sup>+</sup> free radical scavenging rates. FT-IR, <sup>1</sup>H NMR, and computational simulations confirmed the hydrogen-bond network between CA and cellobiose as the core stabilization mechanism. This study provides a novel, eco-friendly strategy for high-performance natural stabilizers, offering the advancement of green, functional delivery systems across relevant industries."],"journal":["Food chemistry: X"],"pagination":["103487"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12814101"],"repository":["biostudies-literature"],"pubmed_title":["Hydrogen-bond-driven stabilization and antioxidant synergy in Pickering emulsions stabilized by natural polyphenol-cellulose nanocrystal hybrids."],"pmcid":["PMC12814101"],"pubmed_authors":["Li W","Yang X","Xie D","Han K","Zou L","Lv Y","Zhao P","Jiang Q","Rao X","Yin L","Xie S"],"additional_accession":[]},"is_claimable":false,"name":"Hydrogen-bond-driven stabilization and antioxidant synergy in Pickering emulsions stabilized by natural polyphenol-cellulose nanocrystal hybrids.","description":"To meet the increasing demand for green and sustainable delivery systems in food, cosmetics, and pharmaceuticals and address the research gap in natural polyphenol-cellulose nanocrystal (CNC) composite stabilizers, this study developed a bio-based Pickering emulsion stabilizer via hydrogen bonding between 6'-<i>O</i>-caffeoylarbutin (CA) and CNCs. Results demonstrated CA/CNCs self-assembled into a dense interfacial layer, endowing the emulsion with exceptional stability that was reflected in over 85% curcumin enscapsulation efficiency after 30 days of dark storage and structural integrity at up to 80 °C, while CA-curcumin synergism enhanced antioxidant activity with 76.9% DPPH and 81.2% ABTS<sup>+</sup> free radical scavenging rates. FT-IR, <sup>1</sup>H NMR, and computational simulations confirmed the hydrogen-bond network between CA and cellobiose as the core stabilization mechanism. This study provides a novel, eco-friendly strategy for high-performance natural stabilizers, offering the advancement of green, functional delivery systems across relevant industries.","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-12T05:12:08.165Z","creation":"2026-06-12T03:07:59.02Z"},"accession":"S-EPMC12814101","cross_references":{"pubmed":["41560896"],"doi":["10.1016/j.fochx.2026.103487"]}}