biostudies-literatureUnknown18(1)Shanshal M<h4>Introduction</h4>Meyerson phenomenon denotes a perilesional, classically eczematous halo around a pre-existing lesion, most often melanocytic. Non-melanocytic halos are uncommon and can mimic regression in a melanocytic lesion, including melanoma, leading to urgent referrals.<h4>Case presentation</h4>We report a 37-year-old woman with a "mole with a halo" on her arm. Examination revealed a 5-mm pink papule with a thin whitish collarette and a faint, ill-defined hypopigmented ring. Dermoscopy showed a structureless pink centre with a pinpoint crust and delicate collarette, but no pigment network or organised vascular pattern. Excisional biopsy revealed a dermal spindle-cell proliferation characteristic of dermatofibroma; the diagnosis was confirmed by negative SOX10 and positive Factor Case reports in dermatology56-63https://www.ebi.ac.uk/biostudies/studies/S-EPMC12818893biostudies-literatureDermatofibroma with Hypopigmented Meyerson Halo: A Case Report and Review of Non-Melanocytic Hosts.PMC12818893Abuayyash MMShanshal MfalseDermatofibroma with Hypopigmented Meyerson Halo: A Case Report and Review of Non-Melanocytic Hosts.<h4>Introduction</h4>Meyerson phenomenon denotes a perilesional, classically eczematous halo around a pre-existing lesion, most often melanocytic. Non-melanocytic halos are uncommon and can mimic regression in a melanocytic lesion, including melanoma, leading to urgent referrals.<h4>Case presentation</h4>We report a 37-year-old woman with a "mole with a halo" on her arm. Examination revealed a 5-mm pink papule with a thin whitish collarette and a faint, ill-defined hypopigmented ring. Dermoscopy showed a structureless pink centre with a pinpoint crust and delicate collarette, but no pigment network or organised vascular pattern. Excisional biopsy revealed a dermal spindle-cell proliferation characteristic of dermatofibroma; the diagnosis was confirmed by negative SOX10 and positive Factor 2026-01-01T00:00:00Z2026 Jan-Dec2026-06-06T19:45:38.265Z2026-06-04T03:12:31.839ZS-EPMC128188934156820010.1159/000549986