{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["61(1)"],"submitter":["Sobieralski P"],"pubmed_abstract":["Outcomes in myelofibrosis (MF) patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT) appear unaffected by the intensity of the preparative regimen, defined traditionally as myeloablative (MAC) or reduced intensity conditioning (RIC). The Transplant Conditioning Intensity (TCI) index is an objective tool offering a precise measure of conditioning intensity. We explored the potential association between TCI score and overall survival (OS), progression-free survival (PFS), cumulative incidence of relapse (CIR) and non-relapse mortality (NRM) in 2454 MF patients undergoing allo-HCT between 2012 and 2021, selected from the EBMT registry. Patients receiving TCI-intermediate/high regimens had similar OS (HR 1.12, 95% CI 0.97-1.30) and PFS (HR 1.00, 95% CI 0.88-1.14) compare"],"journal":["Bone marrow transplantation"],"pagination":["36-43"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12819149"],"repository":["biostudies-literature"],"pubmed_title":["Transplant conditioning intensity (TCI) score predicts allo-HCT outcomes in patients with myelofibrosis: a study of the Chronic Malignancies Working Party of EBMT."],"pmcid":["PMC12819149"],"pubmed_authors":["McLornan DP","Sobieralski P","Schroeder T","Robin M","Battipaglia G","Zaucha J","Broers AEC","Drozd-Sokolowska J","Verbeek M","Czerw T","Yonal-Hindilerden I","Raj K","Metafuni E","Chevallier P","Stelljes M","Zeiser R","Koster L","Friis L","Polverelli N","Passweg J","Rubio MT","Hernandez-Boluda JC","Pastore D","Gras L","Kroger N"],"additional_accession":[]},"is_claimable":false,"name":"Transplant conditioning intensity (TCI) score predicts allo-HCT outcomes in patients with myelofibrosis: a study of the Chronic Malignancies Working Party of EBMT.","description":"Outcomes in myelofibrosis (MF) patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT) appear unaffected by the intensity of the preparative regimen, defined traditionally as myeloablative (MAC) or reduced intensity conditioning (RIC). The Transplant Conditioning Intensity (TCI) index is an objective tool offering a precise measure of conditioning intensity. We explored the potential association between TCI score and overall survival (OS), progression-free survival (PFS), cumulative incidence of relapse (CIR) and non-relapse mortality (NRM) in 2454 MF patients undergoing allo-HCT between 2012 and 2021, selected from the EBMT registry. Patients receiving TCI-intermediate/high regimens had similar OS (HR 1.12, 95% CI 0.97-1.30) and PFS (HR 1.00, 95% CI 0.88-1.14) compare","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-06T18:00:48.577Z","creation":"2026-06-04T03:09:45.197Z"},"accession":"S-EPMC12819149","cross_references":{"pubmed":["41094190"],"doi":["10.1038/s41409-025-02732-w"]}}