biostudies-literatureUnknown46(1)Keil C<h4>Objective</h4>To provide an updated overview of international clinical practice in prenatal repair of open spinal dysraphism (OSD), focusing on evolving eligibility criteria, surgical techniques, and diagnostic standards.<h4>Methods</h4>A structured online survey was distributed to 83 fetal surgery centers worldwide. The questionnaire addressed surgical techniques, maternal and fetal eligibility and diagnostic standards. Descriptive analyses were performed to identify current trends and practice variations.<h4>Results</h4>38 centers from 16 countries participated in the survey (response rate 45.8%). Open fetal surgery remains the most common approach (51.4%) though 47.4% reported offering multiple techniques, including fetoscopic methods. Compared with the MOMS criteria, 42.4% performePrenatal diagnosis75-83https://www.ebi.ac.uk/biostudies/studies/S-EPMC12819936biostudies-literatureEvolving Practices in Prenatal Open Spinal Dysraphism: A Global Survey of Selection Criteria, Surgical Techniques, and Diagnostic Trends.PMC12819936Krispin EWiora NWindhorst ABedei IKeil CAxt-Fliedner RfalseEvolving Practices in Prenatal Open Spinal Dysraphism: A Global Survey of Selection Criteria, Surgical Techniques, and Diagnostic Trends.<h4>Objective</h4>To provide an updated overview of international clinical practice in prenatal repair of open spinal dysraphism (OSD), focusing on evolving eligibility criteria, surgical techniques, and diagnostic standards.<h4>Methods</h4>A structured online survey was distributed to 83 fetal surgery centers worldwide. The questionnaire addressed surgical techniques, maternal and fetal eligibility and diagnostic standards. Descriptive analyses were performed to identify current trends and practice variations.<h4>Results</h4>38 centers from 16 countries participated in the survey (response rate 45.8%). Open fetal surgery remains the most common approach (51.4%) though 47.4% reported offering multiple techniques, including fetoscopic methods. Compared with the MOMS criteria, 42.4% performe2026-01-01T00:00:00Z2026 Jan2026-06-06T19:28:08.179Z2026-06-04T03:10:32.053ZS-EPMC128199364129811310.1002/pd.70031