{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(1)"],"submitter":["Cabre HE"],"pubmed_abstract":["<h4>Background</h4>Total daily energy expenditure (TDEE) is vital for energy balance and cardiometabolic health, yet its trajectory across the lifespan, particularly in females, remains poorly understood.<h4>Objectives</h4>We sought to examine the effects of aging and sex on body composition and TDEE.<h4>Methods</h4>In a cross-sectional analysis of data from research centers across 9 European Countries and the United States from the International Atomic Energy Agency database, TDEE and body composition measures of 2326 participants (1560W/766M; 50.7 ± 12 .6 y) were stratified across age groups: young (30-39 y; YOUNG), middle-aged (40-54 y; MID), and old (55-70 y; OLD). Doubly labeled water was used to estimate TDEE and fat-free mass (FFM). Fat mass (FM) was calculated as the difference bet"],"journal":["Current developments in nutrition"],"pagination":["107614"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12830153"],"repository":["biostudies-literature"],"pubmed_title":["Sex Differences in Measures of Energy Expenditure and Body Composition in Young, Middle-Aged, and Older Adults."],"pmcid":["PMC12830153"],"pubmed_authors":["Arab L","Hu S","Redman LM","Ravussin E","Verbunt JA","Cooper R","Kushner RF","Gurven M","Colbert LH","Wood BM","Loechl CU","Beyl R","Schuit AJ","Sagayama H","Rood J","Marlatt KL","Urlacher SS","Joosen AM","Valencia ME","Sardinha LB","Silva AM","Fernandez-Verdejo R","Reynolds RM","Murphy-Alford AJ","Kriengsinyos W","Bonomi AG","Anderson LJ","Katzmarzyk P","Prentice RL","Luke AH","Casper R","Deb S","Yamada Y","Lessan N","Bovet P","Kraus WE","Cabre HE","Gillingham M","Pontzer H","Ainslie PN","Morehen JC","Camps SG","Bouten CV","Wong WW","Kimura M","Butte NF","Aleman-Mateo H","Schoeller DA","Close GL","Andersen LF","Das SK","Martin CK","Raichlen DA","Van Etten LM","Bedu-Addo K","Forrester T","Morton JP","Speakman JR","Roberts SB","Yoshida T","Brage S","Buchowski MS","Matsiko E","Westerterp KR","Lof M","Kempen KP","Hambly C","Wilson G","Zhang X","Neuhouser ML","Racette SB","Cooper JA","Goris AH","Medin AC"],"additional_accession":[]},"is_claimable":false,"name":"Sex Differences in Measures of Energy Expenditure and Body Composition in Young, Middle-Aged, and Older Adults.","description":"<h4>Background</h4>Total daily energy expenditure (TDEE) is vital for energy balance and cardiometabolic health, yet its trajectory across the lifespan, particularly in females, remains poorly understood.<h4>Objectives</h4>We sought to examine the effects of aging and sex on body composition and TDEE.<h4>Methods</h4>In a cross-sectional analysis of data from research centers across 9 European Countries and the United States from the International Atomic Energy Agency database, TDEE and body composition measures of 2326 participants (1560W/766M; 50.7 ± 12 .6 y) were stratified across age groups: young (30-39 y; YOUNG), middle-aged (40-54 y; MID), and old (55-70 y; OLD). Doubly labeled water was used to estimate TDEE and fat-free mass (FFM). Fat mass (FM) was calculated as the difference bet","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-16T04:45:46.754Z","creation":"2026-06-16T03:06:36.358Z"},"accession":"S-EPMC12830153","cross_references":{"pubmed":["41583128"],"doi":["10.1016/j.cdnut.2025.107614"]}}