{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["43(1)"],"submitter":["Taggi M"],"pubmed_abstract":["<h4>Purpose</h4>To identify treatment-related factors influencing low oocyte maturation rates in standard ovarian stimulation (OS) cycles and patients' candidates for clinical studies on rescue-IVM.<h4>Methods</h4>Retrospective study including retrievals with ≥ 1 cumulus-oocyte-complex (COC; years: 2008-2022). The weighted-mean immaturityrate (19%) was defined in the whole dataset (N = 16,155). Variables associated with immaturity rates and warning limit (defined as weighted average + 2SD) were appraised among first retrievals with ≥ 5 COCs (N = 7962). Of the patients undergoing a first oocyte pick-up, 667 completed three retrieval cycles, enabling evaluation of the true prevalence of patients exceeding the immaturity rate warning threshold over multiple cycles.<h4>Results</h4>Factors infl"],"journal":["Journal of assisted reproduction and genetics"],"pagination":["167-177"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12831772"],"repository":["biostudies-literature"],"pubmed_title":["Rates and risk factors of oocyte immaturity: toward personalized selection for rescue in vitro maturation."],"pmcid":["PMC12831772"],"pubmed_authors":["Coticchio G","Maggiulli R","Taggi M","Soscia DM","Petrone P","Albricci L","Ruffa A","Fiorentino G","Capalbo A","Cimadomo D","Rienzi L","Innocenti F","Casciani V","Cermisoni GC","Zuccotti M","Vaiarelli A"],"additional_accession":[]},"is_claimable":false,"name":"Rates and risk factors of oocyte immaturity: toward personalized selection for rescue in vitro maturation.","description":"<h4>Purpose</h4>To identify treatment-related factors influencing low oocyte maturation rates in standard ovarian stimulation (OS) cycles and patients' candidates for clinical studies on rescue-IVM.<h4>Methods</h4>Retrospective study including retrievals with ≥ 1 cumulus-oocyte-complex (COC; years: 2008-2022). The weighted-mean immaturityrate (19%) was defined in the whole dataset (N = 16,155). Variables associated with immaturity rates and warning limit (defined as weighted average + 2SD) were appraised among first retrievals with ≥ 5 COCs (N = 7962). Of the patients undergoing a first oocyte pick-up, 667 completed three retrieval cycles, enabling evaluation of the true prevalence of patients exceeding the immaturity rate warning threshold over multiple cycles.<h4>Results</h4>Factors infl","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-06T21:58:40.848Z","creation":"2026-06-05T03:12:05.39Z"},"accession":"S-EPMC12831772","cross_references":{"pubmed":["41239007"],"doi":["10.1007/s10815-025-03722-z"]}}