biostudies-literatureUnknown16Huang Q<h4>Background</h4>Ferroptosis is a form of programmed cell death triggered by iron-dependent lipid peroxidation. Accumulating evidence has revealed potential associations between cellular Ferroptosis and infection, inflammation, and immunity. Given the substantial literature in this field, the present study aims to comprehensively overview the research hotspots and knowledge structure underlying the interplay between Ferroptosis and immunity via bibliometric analysis.<h4>Methods</h4>Relevant literature focusing on Ferroptosis and immunity-published between January 1, 2012, and August 31, 2025-was retrieved from the Web of Science, PubMed, and Scopus databases. Bibliometric analyses, encompassing evaluations of national contributions, institutional collaborative networks, journal outputs, Frontiers in immunology1739210https://www.ebi.ac.uk/biostudies/studies/S-EPMC12833263biostudies-literatureFerroptosis and immunity: a bibliometric analysis of research hotspots and frontiers (2012-2025).PMC12833263Guan LHe CGuan JXu RCai YHuang QFeng SWang LfalseFerroptosis and immunity: a bibliometric analysis of research hotspots and frontiers (2012-2025).<h4>Background</h4>Ferroptosis is a form of programmed cell death triggered by iron-dependent lipid peroxidation. Accumulating evidence has revealed potential associations between cellular Ferroptosis and infection, inflammation, and immunity. Given the substantial literature in this field, the present study aims to comprehensively overview the research hotspots and knowledge structure underlying the interplay between Ferroptosis and immunity via bibliometric analysis.<h4>Methods</h4>Relevant literature focusing on Ferroptosis and immunity-published between January 1, 2012, and August 31, 2025-was retrieved from the Web of Science, PubMed, and Scopus databases. Bibliometric analyses, encompassing evaluations of national contributions, institutional collaborative networks, journal outputs, 2025-01-01T00:00:00Z20252026-06-15T06:23:59.198Z2026-06-15T03:08:34.549ZS-EPMC128332634160162910.3389/fimmu.2025.1739210