biostudies-literatureUnknown16Deng Z<h4>Introduction</h4>This study aimed to identify independent risk factors for DKD in T2DM patients and develop a risk prediction model with internal validation.<h4>Methods</h4>We retrospectively collected data from 1,049 T2DM patients undergoing community health checks in Longhua District (2024). Patients were divided into DKD and non-DKD groups, then randomly divided into training (n=735) and validation (n=314) sets in 7:3 ratio.<h4>Results</h4>The results of the binary logistic regression analysis showed that the duration of diabetes (OR 1.037, 95% CI: 1.005-1.07, P = 0.024), BMI (OR 0.869, 95% CI: 0.762-0.992, P = 0.037), Scr (OR 1.019, 95% CI: 1.010-1.028, P = 0.000), WBC (OR 1.141, 95% CI: 1.019-1.279, P = 0.023), and TyG-BMI (OR 1.019, 95% CI: 1.1007-1.030, P = 0.002) were independeFrontiers in endocrinology1708419https://www.ebi.ac.uk/biostudies/studies/S-EPMC12834776biostudies-literatureDevelopment and validation of a model that predicts the risk of diabetic kidney disease in type 2 diabetes mellitus patients: a retrospective study.PMC12834776Yang JDeng ZZhou HfalseDevelopment and validation of a model that predicts the risk of diabetic kidney disease in type 2 diabetes mellitus patients: a retrospective study.<h4>Introduction</h4>This study aimed to identify independent risk factors for DKD in T2DM patients and develop a risk prediction model with internal validation.<h4>Methods</h4>We retrospectively collected data from 1,049 T2DM patients undergoing community health checks in Longhua District (2024). Patients were divided into DKD and non-DKD groups, then randomly divided into training (n=735) and validation (n=314) sets in 7:3 ratio.<h4>Results</h4>The results of the binary logistic regression analysis showed that the duration of diabetes (OR 1.037, 95% CI: 1.005-1.07, P = 0.024), BMI (OR 0.869, 95% CI: 0.762-0.992, P = 0.037), Scr (OR 1.019, 95% CI: 1.010-1.028, P = 0.000), WBC (OR 1.141, 95% CI: 1.019-1.279, P = 0.023), and TyG-BMI (OR 1.019, 95% CI: 1.1007-1.030, P = 0.002) were independe2025-01-01T00:00:00Z20252026-06-13T05:26:07.243Z2026-06-13T03:08:58.162ZS-EPMC128347764160746410.3389/fendo.2025.1708419