{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["57(1)"],"submitter":["Vatandoust S"],"funding":["Flinders University"],"pubmed_abstract":["<h4>Background</h4>Sphincter-preserving surgery for rectal cancer is associated with long-term bowel dysfunction, yet data on outcomes in patients managed with watch-and-wait is limited. This study compared bowel function in rectal cancer survivors managed with watch-and-wait versus sphincter-preserving surgery and evaluated the performance of two instruments: the Memorial Sloan Kettering Bowel Function Instrument (MSK-BFI) and the Low Anterior Resection Syndrome (LARS) score within each cohort.<h4>Patients and methods</h4>In this cross-sectional study, rectal cancer survivors treated with long-course chemoradiotherapy between 2011 and 2019 at Flinders Medical Centre were recruited. Participants without stomas completed the MSK-BFI, LARS, and comorbidity questionnaires. Demographics and cl"],"journal":["Journal of gastrointestinal cancer"],"pagination":["26"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12835014"],"repository":["biostudies-literature"],"pubmed_title":["Bowel Function in Survivors of Rectal Cancer Managed with Watch-and-Wait Versus Surgery."],"pmcid":["PMC12835014"],"pubmed_authors":["Karapetis CS","Vatandoust S","Ullah S","Hollington P","Sposato L","Wattchow D","Leung J","Chen G","Roy A","Michael MZ","de Fontgalland D"],"additional_accession":[]},"is_claimable":false,"name":"Bowel Function in Survivors of Rectal Cancer Managed with Watch-and-Wait Versus Surgery.","description":"<h4>Background</h4>Sphincter-preserving surgery for rectal cancer is associated with long-term bowel dysfunction, yet data on outcomes in patients managed with watch-and-wait is limited. This study compared bowel function in rectal cancer survivors managed with watch-and-wait versus sphincter-preserving surgery and evaluated the performance of two instruments: the Memorial Sloan Kettering Bowel Function Instrument (MSK-BFI) and the Low Anterior Resection Syndrome (LARS) score within each cohort.<h4>Patients and methods</h4>In this cross-sectional study, rectal cancer survivors treated with long-course chemoradiotherapy between 2011 and 2019 at Flinders Medical Centre were recruited. Participants without stomas completed the MSK-BFI, LARS, and comorbidity questionnaires. Demographics and cl","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-10T09:02:42.353Z","creation":"2026-06-10T03:12:06.49Z"},"accession":"S-EPMC12835014","cross_references":{"pubmed":["41586945"],"doi":["10.1007/s12029-025-01389-4"]}}