biostudies-literatureSaito JEiken Chemical Co., Ltd.225https://www.ebi.ac.uk/biostudies/studies/S-EPMC12839786biostudies-literatureUnknown16(2)<b>Background/Objectives:</b> This study examined the clinical utility of diffusion-weighted whole-body magnetic resonance imaging with background body signal suppression (DWIBS) for differentiating infectious from non-infectious aortitis. <b>Methods:</b> The study included 32 patients with suspected inflammatory aortitis who underwent non-contrast computed tomography (NCCT) and magnetic resonance imaging. We evaluated the diagnostic performance of DWIBS using the spinal cord as a reference, NCCT, and their combination. The diagnosis of infectious aortitis was adjudicated based on imaging, clinical, and laboratory findings. We conducted a sensitivity analysis using a stricter definition of infectious aortitis that required both surgical and microbiological confirmation. <b>Results:</b> FifDiagnostics (Basel, Switzerland)Diffusion-Weighted Whole-Body Magnetic Resonance Imaging with Background Body Signal Suppression for Differentiating Infectious from Non-Infectious Aortitis.PMC12839786KY0D020411Asano MNumata YWakasa SYokota ISasaki HSaito JKamiya STada MMuto MHashizume TIwata KfalseDiffusion-Weighted Whole-Body Magnetic Resonance Imaging with Background Body Signal Suppression for Differentiating Infectious from Non-Infectious Aortitis.<b>Background/Objectives:</b> This study examined the clinical utility of diffusion-weighted whole-body magnetic resonance imaging with background body signal suppression (DWIBS) for differentiating infectious from non-infectious aortitis. <b>Methods:</b> The study included 32 patients with suspected inflammatory aortitis who underwent non-contrast computed tomography (NCCT) and magnetic resonance imaging. We evaluated the diagnostic performance of DWIBS using the spinal cord as a reference, NCCT, and their combination. The diagnosis of infectious aortitis was adjudicated based on imaging, clinical, and laboratory findings. We conducted a sensitivity analysis using a stricter definition of infectious aortitis that required both surgical and microbiological confirmation. <b>Results:</b> Fif2026-01-01T00:00:00Z2026 Jan2026-06-14T03:24:09.018Z2026-06-14T03:16:11.124ZS-EPMC128397864159420110.3390/diagnostics16020225