biostudies-literatureUnknown15(2)Paolino G<b>Background</b>: Parasitic skin-related conditions represent a frequent and evolving challenge in human dermatology, as they often mimic other dermatoses, and are increasingly complicated by therapeutic resistance. With this study, we aimed to provide a practical, clinician-oriented overview of our experience, contextualising it within the current literature. <b>Materials and Methods</b>: We conducted a retrospective, single-centre observational study, reporting a case series of 88 patients diagnosed with parasitic or arthropod-related skin infestations at the San Raffaele Hospital Dermatology Unit (Milan) between 2019 and 2024, and integrated a concise narrative review of contemporary evidence on diagnosis, non-invasive imaging and management. For each case, we documented clinical preseJournal of clinical medicine851https://www.ebi.ac.uk/biostudies/studies/S-EPMC12841827biostudies-literatureEctoparasite- and Vector-Borne-Related Dermatoses: A Single-Centre Study with Practical Diagnostic and Management Insights in a One Health Perspective.PMC12841827Valenti MCantisani CZilio DMattozzi CPaolino GGaiera GRongioletti FCarugno ACirami MEsposito GZerbinati NMoroni BCerullo APodo Brunetti AMercuri SRDi Nicola MRfalseEctoparasite- and Vector-Borne-Related Dermatoses: A Single-Centre Study with Practical Diagnostic and Management Insights in a One Health Perspective.<b>Background</b>: Parasitic skin-related conditions represent a frequent and evolving challenge in human dermatology, as they often mimic other dermatoses, and are increasingly complicated by therapeutic resistance. With this study, we aimed to provide a practical, clinician-oriented overview of our experience, contextualising it within the current literature. <b>Materials and Methods</b>: We conducted a retrospective, single-centre observational study, reporting a case series of 88 patients diagnosed with parasitic or arthropod-related skin infestations at the San Raffaele Hospital Dermatology Unit (Milan) between 2019 and 2024, and integrated a concise narrative review of contemporary evidence on diagnosis, non-invasive imaging and management. For each case, we documented clinical prese2026-01-01T00:00:00Z2026 Jan2026-06-13T03:15:03.109Z2026-06-13T03:08:58.774ZS-EPMC128418274159878910.3390/jcm15020851