{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hu H"],"funding":["Key-Area Research and Development Program of Guangdong Province","National Natural Science Foundation of China","Guangdong Province key construction discipline Scientific Research Capacity Improvement Program"],"pagination":["69"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12841978"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(1)"],"pubmed_abstract":["The global migratory pest, <i>Spodoptera frugiperda</i>, has garnered widespread attention due to the serious damage it inflicts on agricultural productivity, particularly in maize. Thymol is a phytochemical that exhibits functional diversification in plant defense, encompassing antibacterial activities and insect pest management. However, the impact of thymol on <i>S. frugiperda</i> is still undetermined. This study examined the growth inhibition and mortality induction in <i>S. frugiperda</i> larvae after thymol exposure. The detrimental effects of 2.0 and 4.0 mg/g thymol treatments on the growth and development of <i>S. frugiperda</i> were also examined. RNA-Seq was used to investigate the probable toxicological mechanism of thymol on <i>S. frugiperda</i>, resulting in the identificatio"],"journal":["Insects"],"pubmed_title":["Growth Inhibition, Mortality Induction, Adverse Impacts of Development, and Underlying Molecular Mechanisms of Thymol Against <i>Spodoptera frugiperda</i>."],"pmcid":["PMC12841978"],"funding_grant_id":["32102221","2020B020223004","2021ZDJS001"],"pubmed_authors":["Shu B","He S","Xie X","Zhang J","Hu H","Sethuraman V","Liu C","Yao H"],"additional_accession":[]},"is_claimable":false,"name":"Growth Inhibition, Mortality Induction, Adverse Impacts of Development, and Underlying Molecular Mechanisms of Thymol Against <i>Spodoptera frugiperda</i>.","description":"The global migratory pest, <i>Spodoptera frugiperda</i>, has garnered widespread attention due to the serious damage it inflicts on agricultural productivity, particularly in maize. Thymol is a phytochemical that exhibits functional diversification in plant defense, encompassing antibacterial activities and insect pest management. However, the impact of thymol on <i>S. frugiperda</i> is still undetermined. This study examined the growth inhibition and mortality induction in <i>S. frugiperda</i> larvae after thymol exposure. The detrimental effects of 2.0 and 4.0 mg/g thymol treatments on the growth and development of <i>S. frugiperda</i> were also examined. RNA-Seq was used to investigate the probable toxicological mechanism of thymol on <i>S. frugiperda</i>, resulting in the identificatio","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-13T03:12:11.993Z","creation":"2026-06-13T03:08:48.112Z"},"accession":"S-EPMC12841978","cross_references":{"pubmed":["41598922"],"doi":["10.3390/insects17010069"]}}