{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wawrzyniak S"],"funding":["Medical University of Silesia"],"pagination":["50"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12842445"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(1)"],"pubmed_abstract":["<b>Background:</b> There exists some inconsistent evidence on the relationship between altered cardiac morphology, its function, and frailty. Therefore, this study aimed to assess the associations among frailty, lean body mass, central arterial stiffness, and cardiac structure and geometry in older people with a normal ejection fraction. <b>Methods:</b> A total of 205 patients >65 years were enrolled into this ancillary analysis of the FRAPICA study and were assessed for frailty with the Fried phenotype scale. Left ventricular dimensions and geometry were assessed with two-dimensional echocardiography. Fat-free mass was measured using three-site skinfold method. Parametric and non-parametric statistics and analysis of covariance were used for statistical calculations. <b>Results:</b> Frail"],"journal":["Journal of cardiovascular development and disease"],"pubmed_title":["The Impact of Frailty on Left Ventricle Mass and Geometry in Elderly Patients with Normal Ejection Fraction: A STROBE-Compliant Cross-Sectional Study."],"pmcid":["PMC12842445"],"funding_grant_id":["PCN-1-235/K/2/K","BNW-1-171/K/3/K","PCN-1-133/K/0/K","PCN-1-236/N/2/K","BNW-1-141/K/5/K"],"pubmed_authors":["Krawiec M","Bartoszek J","Strzelczyk JK","Tomasik A","Ciesla J","Szablewska D","Wawrzyniak S","Janik M","Wojciechowski P","Woloszyn-Horak E","Masternak MM","Dajnowska I","Schulz M"],"additional_accession":[]},"is_claimable":false,"name":"The Impact of Frailty on Left Ventricle Mass and Geometry in Elderly Patients with Normal Ejection Fraction: A STROBE-Compliant Cross-Sectional Study.","description":"<b>Background:</b> There exists some inconsistent evidence on the relationship between altered cardiac morphology, its function, and frailty. Therefore, this study aimed to assess the associations among frailty, lean body mass, central arterial stiffness, and cardiac structure and geometry in older people with a normal ejection fraction. <b>Methods:</b> A total of 205 patients >65 years were enrolled into this ancillary analysis of the FRAPICA study and were assessed for frailty with the Fried phenotype scale. Left ventricular dimensions and geometry were assessed with two-dimensional echocardiography. Fat-free mass was measured using three-site skinfold method. Parametric and non-parametric statistics and analysis of covariance were used for statistical calculations. <b>Results:</b> Frail","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-12T03:16:53.694Z","creation":"2026-06-12T03:11:27.695Z"},"accession":"S-EPMC12842445","cross_references":{"pubmed":["41590877"],"doi":["10.3390/jcdd13010050"]}}