{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hou L"],"funding":["Mingchang Chang","Ludan Hou"],"pagination":["48"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12843154"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(1)"],"pubmed_abstract":["In recent years, the response mechanism of <i>Pleurotus ostreatus</i> to abiotic stress has received widespread attention. MnSOD is an important antioxidant enzyme that has been widely studied in animals and plants because of its functions. However, there is little research on the function and regulatory mechanism of MnSOD in the growth and development of edible fungi. This study investigated the role of <i>Mnsod3</i> in the growth and development of <i>P. ostreatus</i>. The results showed that during the nutritional growth stage, heat stress can cause the cell wall of mycelia to shrink and the cells to exhibit cytoplasmic wall separation. RNA-seq revealed that <i>Mnsod3</i> interference is strongly correlated with increased transcript levels of cell wall synthase genes and with increased "],"journal":["Journal of fungi (Basel, Switzerland)"],"pubmed_title":["The Interference of <i>Mnsod3</i> Enhances the Tolerance of <i>Pleurotus ostreatus</i> Mycelia to Abiotic Stress by Reshaping the Cell Wall."],"pmcid":["PMC12843154"],"funding_grant_id":["202301140601015","32402654","2021BQ90","SXBYK2022029"],"pubmed_authors":["Hou L","Deng B","Xu L","Chang M","Li T","Zhang Z","Geng X","Meng J","Zhang B","Cheng Y"],"additional_accession":[]},"is_claimable":false,"name":"The Interference of <i>Mnsod3</i> Enhances the Tolerance of <i>Pleurotus ostreatus</i> Mycelia to Abiotic Stress by Reshaping the Cell Wall.","description":"In recent years, the response mechanism of <i>Pleurotus ostreatus</i> to abiotic stress has received widespread attention. MnSOD is an important antioxidant enzyme that has been widely studied in animals and plants because of its functions. However, there is little research on the function and regulatory mechanism of MnSOD in the growth and development of edible fungi. This study investigated the role of <i>Mnsod3</i> in the growth and development of <i>P. ostreatus</i>. The results showed that during the nutritional growth stage, heat stress can cause the cell wall of mycelia to shrink and the cells to exhibit cytoplasmic wall separation. RNA-seq revealed that <i>Mnsod3</i> interference is strongly correlated with increased transcript levels of cell wall synthase genes and with increased ","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-14T03:20:41.75Z","creation":"2026-06-14T03:14:54.868Z"},"accession":"S-EPMC12843154","cross_references":{"pubmed":["41590460"],"doi":["10.3390/jof12010048"]}}