biostudies-literatureHung NAMinistry of Education and Training357https://www.ebi.ac.uk/biostudies/studies/S-EPMC12843715biostudies-literatureUnknown31(2)The present study involves the isolation, structural elucidation, and biological evaluation of eight compounds from <i>Pouzolzia zeylanica</i>. From the <i>n</i>-hexane and ethyl acetate extracts of the plant, eight compounds were successfully isolated and identified: oleanolic acid (<b>1</b>), ursolic acid (<b>2</b>), 2<i>α</i>-hydroxyursolic acid (<b>3</b>), 3<i>β</i>-O-acetyl-12-oleanen-28-oic acid (<b>4</b>), 5-hydroxy-6,7-dimethoxyflavanone (<b>5</b>), 4'-methoxytectochrysin (<b>6</b>), 3,4',5,7-tetrahydroxyflavanone-3-O-L-rhamnopyranoside (<b>7</b>), and 3,3',5,5',7-pentahydroxyflavanone-3-O-L-rhamnopyranoside (<b>8</b>). These compounds were evaluated for in vitro antioxidant activity using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and lipid peroxidation inhibition (TBARS) assays, asMolecules (Basel, Switzerland)In Silico and In Vitro Insights into the Pharmacological Potential of <i>Pouzolzia zeylanica</i>.PMC12843715B2022-SP2-07Le VTTTam HTMLam DTHop NQHung NVHanh NTHung NALinh NNfalseIn Silico and In Vitro Insights into the Pharmacological Potential of <i>Pouzolzia zeylanica</i>.The present study involves the isolation, structural elucidation, and biological evaluation of eight compounds from <i>Pouzolzia zeylanica</i>. From the <i>n</i>-hexane and ethyl acetate extracts of the plant, eight compounds were successfully isolated and identified: oleanolic acid (<b>1</b>), ursolic acid (<b>2</b>), 2<i>α</i>-hydroxyursolic acid (<b>3</b>), 3<i>β</i>-O-acetyl-12-oleanen-28-oic acid (<b>4</b>), 5-hydroxy-6,7-dimethoxyflavanone (<b>5</b>), 4'-methoxytectochrysin (<b>6</b>), 3,4',5,7-tetrahydroxyflavanone-3-O-L-rhamnopyranoside (<b>7</b>), and 3,3',5,5',7-pentahydroxyflavanone-3-O-L-rhamnopyranoside (<b>8</b>). These compounds were evaluated for in vitro antioxidant activity using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and lipid peroxidation inhibition (TBARS) assays, as2026-01-01T00:00:00Z2026 Jan2026-06-11T03:11:09.274Z2026-06-11T03:08:09.554ZS-EPMC128437154159940510.3390/molecules31020357