biostudies-literatureCui CFinancial Science and Technology Program of the Corps - Key Field Science and Technology Research Program175https://www.ebi.ac.uk/biostudies/studies/S-EPMC12845441biostudies-literatureUnknown15(2)The nitrate signaling core regulator <i>NLP7</i> is known to negatively regulate salt tolerance in <i>Arabidopsis thaliana</i>, but the function of the (<i>SsNLP7A</i>) gene in the halophyte <i>Suaeda salsa</i> remains unclear. To investigate whether <i>SsNLP7A</i> participates in salt stress responses, this study heterologously overexpressed the gene in tomato (<i>Solanum lycopersicum</i>) and systematically evaluated its function under salt stress through phenotypic, physiological, and transcriptomic analyses. The results indicate that <i>SsNLP7A</i> overexpression significantly promotes tomato root development and alleviates growth inhibition caused by salt stress. Under salt treatment, transgenic plants exhibited significantly higher chlorophyll content, accumulation of osmotic regulatPlants (Basel, Switzerland)Expression of the <i>Suaeda salsa SsNLP7</i> Transcription Factor in <i>Solanum lycopersicum</i> Enhances Its Salt Tolerance.PMC128454412023AB006-02Xiong YZhu JWang SChen YCui CWu XfalseExpression of the <i>Suaeda salsa SsNLP7</i> Transcription Factor in <i>Solanum lycopersicum</i> Enhances Its Salt Tolerance.The nitrate signaling core regulator <i>NLP7</i> is known to negatively regulate salt tolerance in <i>Arabidopsis thaliana</i>, but the function of the (<i>SsNLP7A</i>) gene in the halophyte <i>Suaeda salsa</i> remains unclear. To investigate whether <i>SsNLP7A</i> participates in salt stress responses, this study heterologously overexpressed the gene in tomato (<i>Solanum lycopersicum</i>) and systematically evaluated its function under salt stress through phenotypic, physiological, and transcriptomic analyses. The results indicate that <i>SsNLP7A</i> overexpression significantly promotes tomato root development and alleviates growth inhibition caused by salt stress. Under salt treatment, transgenic plants exhibited significantly higher chlorophyll content, accumulation of osmotic regulat2026-01-01T00:00:00Z2026 Jan2026-06-08T03:31:40.028Z2026-06-08T03:14:41.64ZS-EPMC128454414159998110.3390/plants15020175