biostudies-literatureUnknown18(1)Kelman MJ<i>Ramaria flavobrunnescens</i> is an ectomycorrhizal coral mushroom that is often found growing in eucalyptus forests. The mushroom has been linked to accidental ingestion-associated livestock poisonings in South America, though the toxicological agent has not yet been described. Mushroom samples identified as <i>R. flavobrunnescens</i> were analyzed by liquid chromatography high-resolution mass spectrometry (LC-MS/MS) to determine the potential source of the toxicity, and to provide a metabolomic profile of the species. Previously reported <i>Ramaria</i> secondary metabolites were detected, including ramarins, ramariolides, pistillarin and arsenic-containing compounds. A number of bacterial species were isolated from <i>R. flavobrunnescens</i> that produced iron-chelating cyclic peptidesToxins53https://www.ebi.ac.uk/biostudies/studies/S-EPMC12845983biostudies-literatureHigh-Resolution LC-MS Characterization of <i>Ramaria flavobrunnescens,</i> a Coral Mushroom Toxic to Livestock, Reveals Fungal, Bacterial, and Eucalyptus Tree Metabolites.PMC12845983Sumarah MWRenaud JBKelman MJTanney JBMachado MfalseHigh-Resolution LC-MS Characterization of <i>Ramaria flavobrunnescens,</i> a Coral Mushroom Toxic to Livestock, Reveals Fungal, Bacterial, and Eucalyptus Tree Metabolites.<i>Ramaria flavobrunnescens</i> is an ectomycorrhizal coral mushroom that is often found growing in eucalyptus forests. The mushroom has been linked to accidental ingestion-associated livestock poisonings in South America, though the toxicological agent has not yet been described. Mushroom samples identified as <i>R. flavobrunnescens</i> were analyzed by liquid chromatography high-resolution mass spectrometry (LC-MS/MS) to determine the potential source of the toxicity, and to provide a metabolomic profile of the species. Previously reported <i>Ramaria</i> secondary metabolites were detected, including ramarins, ramariolides, pistillarin and arsenic-containing compounds. A number of bacterial species were isolated from <i>R. flavobrunnescens</i> that produced iron-chelating cyclic peptides2026-01-01T00:00:00Z2026 Jan2026-06-09T03:19:37.054Z2026-06-09T03:12:06.689ZS-EPMC128459834159119910.3390/toxins18010053