{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17"],"submitter":["Jabbari-Zadeh F"],"pubmed_abstract":["Warm autoimmune hemolytic anemia (wAIHA) is characterized by autoantibodies against proteins that comprise the Rh antigen system along with hemolysis. The presence of specific autoantibodies, especially autoantibodies with anti-e specificity, is rare. The pathophysiology, management, and outcomes in this condition, including with transfusion of e-antigen positive packed red blood cells (pRBCs), remain poorly understood. A 63-year-old woman presented with fatigue, jaundice, tea-colored urine, and dyspnea. She was diagnosed with wAIHA with anti-e specificity and developed worsening hemolysis after receiving a unit of e-antigen positive pRBCs with a drop in hemoglobin from 85 to 71 g/L. She achieved a complete response with a tapering course of prednisone and folate. We conducted a systematic"],"journal":["Therapeutic advances in hematology"],"pagination":["20406207251410168"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12847652"],"repository":["biostudies-literature"],"pubmed_title":["Transfusion-induced hemolysis in warm autoimmune hemolytic anemia with autoantibodies that have anti-e specificity: a case report and systematic review of the literature."],"pmcid":["PMC12847652"],"pubmed_authors":["Jabbari-Zadeh F","Solh Z","Chin-Yee B","Gob A","Hoxha O","Hsia CC"],"additional_accession":[]},"is_claimable":false,"name":"Transfusion-induced hemolysis in warm autoimmune hemolytic anemia with autoantibodies that have anti-e specificity: a case report and systematic review of the literature.","description":"Warm autoimmune hemolytic anemia (wAIHA) is characterized by autoantibodies against proteins that comprise the Rh antigen system along with hemolysis. The presence of specific autoantibodies, especially autoantibodies with anti-e specificity, is rare. The pathophysiology, management, and outcomes in this condition, including with transfusion of e-antigen positive packed red blood cells (pRBCs), remain poorly understood. A 63-year-old woman presented with fatigue, jaundice, tea-colored urine, and dyspnea. She was diagnosed with wAIHA with anti-e specificity and developed worsening hemolysis after receiving a unit of e-antigen positive pRBCs with a drop in hemoglobin from 85 to 71 g/L. She achieved a complete response with a tapering course of prednisone and folate. We conducted a systematic","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026","modification":"2026-06-11T05:34:01.073Z","creation":"2026-06-11T03:08:15.468Z"},"accession":"S-EPMC12847652","cross_references":{"pubmed":["41613625"],"doi":["10.1177/20406207251410168"]}}