{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(1)"],"submitter":["Wang Y"],"funding":["Yangzhou University Interdisciplinary Research Foundation for Veterinary Medicine Discipline of Targeted Support","National Key Research and Development Program of China"],"pubmed_abstract":["Migratory birds are key vectors of pathogens and antibiotic-resistance genes (ARGs), yet intrapopulation variation and its microbiome-mediated basis remain poorly understood. Here, we characterized the gut microbiome of 70 individuals from a migratory Anser serrirostris population using full-length 16S rDNA sequencing, followed by metagenomic analysis of 25 representative samples. Both approaches consistently identified two distinct groups (E1 and E2). Network analysis revealed impaired microbial interactions in E1 compared to E2. E1 exhibited higher abundances of opportunistic pathogens (e.g., Pseudomonas, Erwinia) and enriched functions related to pathogenicity and ARGs, predominantly driven by these taxa. Conversely, E2 showed function enrichment in short-chain fatty acid biosynthesis a"],"journal":["NPJ biofilms and microbiomes"],"pagination":["22"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12847833"],"repository":["biostudies-literature"],"pubmed_title":["Gut microbiome profiling of a migratory Anser serrirostris population reveals two groups with distinct pathogen and ARG contents."],"pmcid":["PMC12847833"],"pubmed_authors":["Liang S","Huang J","Wang E","Chen H","Wang J","Xu J","Zhao Y","Sun L","Hou M","Liang G","Zhang Y","Chen W","Wang Y","Jiao X"],"additional_accession":[]},"is_claimable":false,"name":"Gut microbiome profiling of a migratory Anser serrirostris population reveals two groups with distinct pathogen and ARG contents.","description":"Migratory birds are key vectors of pathogens and antibiotic-resistance genes (ARGs), yet intrapopulation variation and its microbiome-mediated basis remain poorly understood. Here, we characterized the gut microbiome of 70 individuals from a migratory Anser serrirostris population using full-length 16S rDNA sequencing, followed by metagenomic analysis of 25 representative samples. Both approaches consistently identified two distinct groups (E1 and E2). Network analysis revealed impaired microbial interactions in E1 compared to E2. E1 exhibited higher abundances of opportunistic pathogens (e.g., Pseudomonas, Erwinia) and enriched functions related to pathogenicity and ARGs, predominantly driven by these taxa. Conversely, E2 showed function enrichment in short-chain fatty acid biosynthesis a","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-11T05:35:19.427Z","creation":"2026-06-11T03:08:26.373Z"},"accession":"S-EPMC12847833","cross_references":{"pubmed":["41422269"],"doi":["10.1038/s41522-025-00888-3"]}}