{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["105(4)"],"submitter":["Bokhari SFH"],"pubmed_abstract":["<h4>Background</h4>Atrial fibrillation (AF) remains the most common sustained cardiac arrhythmia. Pulsed field ablation (PFA) and cryoablation (CA) aim to isolate pulmonary veins and prevent AF recurrence. This meta-analysis aims to provide a comprehensive comparison of PFA and CA in treatment of AF in context of efficacy, procedural characteristics, and safety profiles.<h4>Methods</h4>A comprehensive literature search of databases (PubMed, Cochrane Library, Science Direct and Google Scholar) was conducted from their inception to September 2024. Statistical analyses were conducted using Cochrane's RevMan 5.4 software.<h4>Results</h4>Twenty studies (n = 4638; PFA = 2172, CA = 3033) were included in this meta-analysis. Regarding efficacy outcomes, PFA significantly reduced AF recurrence (odd"],"journal":["Medicine"],"pagination":["e47353"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12851682"],"repository":["biostudies-literature"],"pubmed_title":["Safety and efficacy of pulsed field ablation versus cryoablation for atrial fibrillation: A comprehensive meta-analysis."],"pmcid":["PMC12851682"],"pubmed_authors":["Asif A","Waleed M","Mubashir MM","Sana H","Bakht D","Iqbal A","Ali K","Qureshi MA","Ali MKB","Hassan A","Awais MN","Bokhari SFH","Amir M"],"additional_accession":[]},"is_claimable":false,"name":"Safety and efficacy of pulsed field ablation versus cryoablation for atrial fibrillation: A comprehensive meta-analysis.","description":"<h4>Background</h4>Atrial fibrillation (AF) remains the most common sustained cardiac arrhythmia. Pulsed field ablation (PFA) and cryoablation (CA) aim to isolate pulmonary veins and prevent AF recurrence. This meta-analysis aims to provide a comprehensive comparison of PFA and CA in treatment of AF in context of efficacy, procedural characteristics, and safety profiles.<h4>Methods</h4>A comprehensive literature search of databases (PubMed, Cochrane Library, Science Direct and Google Scholar) was conducted from their inception to September 2024. Statistical analyses were conducted using Cochrane's RevMan 5.4 software.<h4>Results</h4>Twenty studies (n = 4638; PFA = 2172, CA = 3033) were included in this meta-analysis. Regarding efficacy outcomes, PFA significantly reduced AF recurrence (odd","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-14T05:45:29.563Z","creation":"2026-06-14T03:08:47.597Z"},"accession":"S-EPMC12851682","cross_references":{"pubmed":["41578543"],"doi":["10.1097/MD.0000000000047353"]}}