{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["41(3)"],"submitter":["Plonsky Toder M"],"funding":["Technion - Israel Institute of Technology"],"pubmed_abstract":["<h4>Background</h4>Takayasu arteritis (TAK) is a granulomatous large-vessel vasculitis typically affecting young adult females. Pediatric cases are rare, and infantile onset is exceptional. Management relies on immunosuppression, with surgery reserved for severe complications.<h4>Case report</h4>We describe a now 5.5-year-old boy diagnosed with TAK at six months of age, presenting with hypertensive encephalopathy and kidney dysfunction. Despite treatment with corticosteroids and anti-TNFα, his kidney function deteriorated, leading to kidney failure and dialysis. At nearly three years of age, he underwent abdominal aorto-aortic bypass and bilateral nephrectomy due to progressive vascular narrowing and refractory hypertension. At age four, he successfully received a deceased-donor kidney tra"],"journal":["Pediatric nephrology (Berlin, Germany)"],"pagination":["873-881"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12852304"],"repository":["biostudies-literature"],"pubmed_title":["Navigating complex clinical decisions: kidney transplantation following abdominal aorto-aortic bypass in infantile Takayasu arteritis."],"pmcid":["PMC12852304"],"pubmed_authors":["Plonsky Toder M","Magen D","Tibi R","Steinberg R","Karram T","Eisenstein I","Coleman D","Pollack S","Libinson-Zebegret I","Hoffman A","Yakubov R"],"additional_accession":[]},"is_claimable":false,"name":"Navigating complex clinical decisions: kidney transplantation following abdominal aorto-aortic bypass in infantile Takayasu arteritis.","description":"<h4>Background</h4>Takayasu arteritis (TAK) is a granulomatous large-vessel vasculitis typically affecting young adult females. Pediatric cases are rare, and infantile onset is exceptional. Management relies on immunosuppression, with surgery reserved for severe complications.<h4>Case report</h4>We describe a now 5.5-year-old boy diagnosed with TAK at six months of age, presenting with hypertensive encephalopathy and kidney dysfunction. Despite treatment with corticosteroids and anti-TNFα, his kidney function deteriorated, leading to kidney failure and dialysis. At nearly three years of age, he underwent abdominal aorto-aortic bypass and bilateral nephrectomy due to progressive vascular narrowing and refractory hypertension. At age four, he successfully received a deceased-donor kidney tra","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Mar","modification":"2026-06-16T03:16:01.752Z","creation":"2026-06-16T03:09:42.138Z"},"accession":"S-EPMC12852304","cross_references":{"pubmed":["40932502"],"doi":["10.1007/s00467-025-06932-w"]}}