{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Nan H"],"pubmed_abstract":["The MADS-box gene family plays a central role in plant development and adaptation, yet its evolutionary history in legumes is remarkably complex. In this study, we performed a pangenomic analysis across 52 legume species, identifying 4,872 MADS-box genes and reconstructing their phylogeny into 16 subfamilies. Our analysis uncovered a pervasive dualistic evolutionary model driven by distinct duplication mechanisms. Structurally, the genes fall into two categories: the compact, intron-poor Type I and the complex, intron-rich Type II. We demonstrate that whole-genome duplication (WGD) serves as the major driver (42.2%) behind the expansion of the conserved core genome, which includes key floral regulators such as the \"ABCDE model\" genes. These WGD-derived genes are under strong purifying sele"],"journal":["Frontiers in plant science"],"pagination":["1740598"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12853372"],"repository":["biostudies-literature"],"pubmed_title":["Dualistic MADS-box evolution forged legume diversity post-WGD."],"pmcid":["PMC12853372"],"pubmed_authors":["Zhang J","Zou M","Guo X","Kou K","Nan H","Chen X","Shang E"],"additional_accession":[]},"is_claimable":false,"name":"Dualistic MADS-box evolution forged legume diversity post-WGD.","description":"The MADS-box gene family plays a central role in plant development and adaptation, yet its evolutionary history in legumes is remarkably complex. In this study, we performed a pangenomic analysis across 52 legume species, identifying 4,872 MADS-box genes and reconstructing their phylogeny into 16 subfamilies. Our analysis uncovered a pervasive dualistic evolutionary model driven by distinct duplication mechanisms. Structurally, the genes fall into two categories: the compact, intron-poor Type I and the complex, intron-rich Type II. We demonstrate that whole-genome duplication (WGD) serves as the major driver (42.2%) behind the expansion of the conserved core genome, which includes key floral regulators such as the \"ABCDE model\" genes. These WGD-derived genes are under strong purifying sele","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-20T03:20:07.986Z","creation":"2026-06-20T03:09:44.308Z"},"accession":"S-EPMC12853372","cross_references":{"pubmed":["41626333"],"doi":["10.3389/fpls.2025.1740598"]}}