{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li H"],"funding":["Beijing Municipal Education Commission","Capital Medical University","Beijing Nova Program","National Natural Science Foundation of China"],"pagination":["102550"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12856461"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5(2)"],"pubmed_abstract":["<h4>Background</h4>Healthy sleep is a multidimensional behavior critical for chronic disease prevention, yet its long-term impact on mortality and life expectancy-particularly among individuals with atherosclerotic cardiovascular disease (ASCVD)-remains unclear.<h4>Objectives</h4>The purpose of this study was to evaluate the associations between sleep patterns and mortality and life expectancy among adults with and without ASCVD.<h4>Methods</h4>We analyzed data from 148,622 U.S. adults (mean age 48.4 years, 50.6% female) in the National Health Interview Survey (2013-2018), with mortality follow-up through December 31, 2019. A composite sleep score based on 5 self-reported behaviors was constructed to categorize participants as having poor, intermediate, or healthy sleep patterns. Multivariable Cox models estimated hazard ratios (HRs) for all-cause mortality, and life expectancy was calculated using a flexible parametric survival model.<h4>Results</h4>Over a median 4.3 years of follow-up (IQR: 2.8-5.5), 5,643 deaths occurred. Compared with those with poor sleep patterns, participants with healthy sleep patterns had significantly lower all-cause mortality, both among individuals with ASCVD (HR 0.74, 95% CI: 0.62-0.89) and those without ASCVD (HR 0.82, 95% CI: 0.70-0.95; P for additive interaction = 0.03). At age 45, a healthy sleep pattern was associated with an estimated life expectancy gain of 3.0 years (95% CI: 1.1-4.8) among individuals with ASCVD, and 1.5 years (95% CI: 0.3-2.6) among those without.<h4>Conclusions</h4>Multidimensional healthy sleep patterns are associated with lower mortality and increased life expectancy in adults, with greater absolute benefits observed in individuals with ASCVD."],"journal":["JACC. Advances"],"pubmed_title":["Healthy Sleep Patterns, Mortality, and Life Expectancy in Adults With and Without Atherosclerotic Cardiovascular Disease."],"pmcid":["PMC12856461"],"funding_grant_id":["CYFH202310","KM202210025015","20250484858","72474142","82103942"],"pubmed_authors":["Li H","Liu Y","Li X","Wu Z","Zheng Y","Zhao L","Guo Z","Sun B","Guo X","Sheng C","Zheng D"],"additional_accession":[]},"is_claimable":false,"name":"Healthy Sleep Patterns, Mortality, and Life Expectancy in Adults With and Without Atherosclerotic Cardiovascular Disease.","description":"<h4>Background</h4>Healthy sleep is a multidimensional behavior critical for chronic disease prevention, yet its long-term impact on mortality and life expectancy-particularly among individuals with atherosclerotic cardiovascular disease (ASCVD)-remains unclear.<h4>Objectives</h4>The purpose of this study was to evaluate the associations between sleep patterns and mortality and life expectancy among adults with and without ASCVD.<h4>Methods</h4>We analyzed data from 148,622 U.S. adults (mean age 48.4 years, 50.6% female) in the National Health Interview Survey (2013-2018), with mortality follow-up through December 31, 2019. A composite sleep score based on 5 self-reported behaviors was constructed to categorize participants as having poor, intermediate, or healthy sleep patterns. Multivariable Cox models estimated hazard ratios (HRs) for all-cause mortality, and life expectancy was calculated using a flexible parametric survival model.<h4>Results</h4>Over a median 4.3 years of follow-up (IQR: 2.8-5.5), 5,643 deaths occurred. Compared with those with poor sleep patterns, participants with healthy sleep patterns had significantly lower all-cause mortality, both among individuals with ASCVD (HR 0.74, 95% CI: 0.62-0.89) and those without ASCVD (HR 0.82, 95% CI: 0.70-0.95; P for additive interaction = 0.03). At age 45, a healthy sleep pattern was associated with an estimated life expectancy gain of 3.0 years (95% CI: 1.1-4.8) among individuals with ASCVD, and 1.5 years (95% CI: 0.3-2.6) among those without.<h4>Conclusions</h4>Multidimensional healthy sleep patterns are associated with lower mortality and increased life expectancy in adults, with greater absolute benefits observed in individuals with ASCVD.","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-14T06:01:45.606Z","creation":"2026-06-14T03:16:44.014Z"},"accession":"S-EPMC12856461","cross_references":{"pubmed":["41558361"],"doi":["10.1016/j.jacadv.2025.102550"]}}