{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(1)"],"submitter":["Tavakoli NP"],"pubmed_abstract":["<h4>Importance</h4>Congenital cytomegalovirus (cCMV) is the most common nongenetic cause of sensorineural hearing loss in children and a cause of long-term neurological disabilities. In the absence of universal screening, cCMV disease in many newborns will go undiagnosed and untreated.<h4>Objective</h4>To determine the feasibility, screen-positive rate, and parental acceptance of newborn screening for cCMV using dried blood spot (DBS) specimens.<h4>Design, setting, and participants</h4>In this population-based diagnostic study, newborns whose DBS specimens were submitted to the New York State Newborn Screening Program from October 2, 2023, through September 30, 2024, for routine screening were also screened for CMV. Parents were given the option to opt out of receiving CMV results. Infecti"],"journal":["JAMA network open"],"pagination":["e2554518"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12856680"],"repository":["biostudies-literature"],"pubmed_title":["Universal Newborn Screening for Congenital Cytomegalovirus Using Dried Blood Spot Specimens."],"pmcid":["PMC12856680"],"pubmed_authors":["Caggana M","John M","Ojukwu I","Taormina G","Bradley S","DiAntonio L","Steen L","Nachman S","Kay DM","Hymes S","Giacinto A","Salvatore CM","DeLaMora P","Brandon CJ","Daniel JM","Ungar SP","Saavedra-Matiz C","Daniels D","Rebello G","St-Pierre M","Nolan SM","Nayak JL","Weiner LB","Quinn M","Tavakoli NP","Sack V","Sood S","Handel AS","Weinberg GA","McManaman C","Hicar MD","Pearce M","Piwoz JA"],"additional_accession":[]},"is_claimable":false,"name":"Universal Newborn Screening for Congenital Cytomegalovirus Using Dried Blood Spot Specimens.","description":"<h4>Importance</h4>Congenital cytomegalovirus (cCMV) is the most common nongenetic cause of sensorineural hearing loss in children and a cause of long-term neurological disabilities. In the absence of universal screening, cCMV disease in many newborns will go undiagnosed and untreated.<h4>Objective</h4>To determine the feasibility, screen-positive rate, and parental acceptance of newborn screening for cCMV using dried blood spot (DBS) specimens.<h4>Design, setting, and participants</h4>In this population-based diagnostic study, newborns whose DBS specimens were submitted to the New York State Newborn Screening Program from October 2, 2023, through September 30, 2024, for routine screening were also screened for CMV. Parents were given the option to opt out of receiving CMV results. Infecti","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-13T05:30:51.705Z","creation":"2026-06-13T03:09:20.41Z"},"accession":"S-EPMC12856680","cross_references":{"pubmed":["41609826"],"doi":["10.1001/jamanetworkopen.2025.54518"]}}