{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Leybourne N"],"funding":["Engineering and Physical Sciences Research Council"],"pagination":["13"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12858686"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(1)"],"pubmed_abstract":["<h4>Background</h4>The adoption of silicon photomultiplier (SiPM) detectors over conventional photomultiplier tubes (PMTs) in Positron Emission Tomography (PET) has enhanced overall system performance. In this phantom study, small-lesion detectability was assessed for SiPM-based and PMT-based PET systems for various inhomogeneity sizes, acquisition times and activity contrasts between the inhomogeneity and background.<h4>Methods</h4>Six spheres of internal diameters ranging between 4.0 mm and 13.0 mm were integrated into a NEMA/IEC PET Body Phantom and filled with fluorodeoxyglucose, with a sphere activity concentration of 29.2 MBq/L and five sphere-to-background activity concentration ratios between 4 and 20. Scans were performed with an SiPM-based system and a PMT-based PET system for ea"],"journal":["EJNMMI physics"],"pubmed_title":["Assessing small-lesion detectability and acquisition time optimisation in silicon-detector-Based PET: a phantom study."],"pmcid":["PMC12858686"],"funding_grant_id":["2594498"],"pubmed_authors":["Leybourne N","Evans P","Strouhal P","Prakash V","Hussein M","Fenwick A","Florescu L"],"additional_accession":[]},"is_claimable":false,"name":"Assessing small-lesion detectability and acquisition time optimisation in silicon-detector-Based PET: a phantom study.","description":"<h4>Background</h4>The adoption of silicon photomultiplier (SiPM) detectors over conventional photomultiplier tubes (PMTs) in Positron Emission Tomography (PET) has enhanced overall system performance. In this phantom study, small-lesion detectability was assessed for SiPM-based and PMT-based PET systems for various inhomogeneity sizes, acquisition times and activity contrasts between the inhomogeneity and background.<h4>Methods</h4>Six spheres of internal diameters ranging between 4.0 mm and 13.0 mm were integrated into a NEMA/IEC PET Body Phantom and filled with fluorodeoxyglucose, with a sphere activity concentration of 29.2 MBq/L and five sphere-to-background activity concentration ratios between 4 and 20. Scans were performed with an SiPM-based system and a PMT-based PET system for ea","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-10T08:55:36.536Z","creation":"2026-06-10T03:12:40.273Z"},"accession":"S-EPMC12858686","cross_references":{"pubmed":["41456236"],"doi":["10.1186/s40658-025-00821-9"]}}