{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Su J"],"funding":["USDA-NIFA","NHLBI NIH HHS","National Institutes of Health","NIH HHS","NIGMS NIH HHS","National Science Foundation"],"pagination":["koaf292"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12862871"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["38(1)"],"pubmed_abstract":["Primary root growth, regulated by internal hormone signals, adapts to external factors such as water availability, soil compactness, and microbial interactions. An essential step in root growth consists of cell divisions in the meristem, with the outermost root cap layer thought to provide protection. However, recent studies reveal that lateral root cap (LRC) cells control meristem size and lateral root initiation. In this study, we identified an upper LRC-specific protein condensation mechanism involving SUPPRESSOR of rps4-RLD1 (SRFR1) that governs root growth and show that growth conditions and hormone treatment dynamically modulate condensate accumulation. SRFR1 condensate formation is driven by its plant-associated N-terminal tetratricopeptide repeat (PANT) polymerization domain and fi"],"journal":["The Plant cell"],"pubmed_title":["Polymerization-mediated SRFR1 condensation in upper lateral root cap cells regulates root growth."],"pmcid":["PMC12862871"],"funding_grant_id":["IOS-1456181","1R01HL119053","R35GM136409","R35 GM136409","R01 HL119053","PBI 2022-11933"],"pubmed_authors":["Chen SY","Zhou R","Cseke LJ","Yang B","Su J","Rodriguez-Lukey K","Gassmann W","Zou X","Whittier SK","Baik JS","Picking WD","Zhang Z","Dietz ZK","Xu X"],"additional_accession":[]},"is_claimable":false,"name":"Polymerization-mediated SRFR1 condensation in upper lateral root cap cells regulates root growth.","description":"Primary root growth, regulated by internal hormone signals, adapts to external factors such as water availability, soil compactness, and microbial interactions. An essential step in root growth consists of cell divisions in the meristem, with the outermost root cap layer thought to provide protection. However, recent studies reveal that lateral root cap (LRC) cells control meristem size and lateral root initiation. In this study, we identified an upper LRC-specific protein condensation mechanism involving SUPPRESSOR of rps4-RLD1 (SRFR1) that governs root growth and show that growth conditions and hormone treatment dynamically modulate condensate accumulation. SRFR1 condensate formation is driven by its plant-associated N-terminal tetratricopeptide repeat (PANT) polymerization domain and fi","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-21T03:20:28.705Z","creation":"2026-06-21T03:12:12.419Z"},"accession":"S-EPMC12862871","cross_references":{"pubmed":["41468158"],"doi":["10.1093/plcell/koaf292"]}}