{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kunzel SH"],"funding":["NEI NIH HHS","National Eye Institute","DFG","Research to Prevent Blindness","University of Bonn","National Institutes of Health"],"pagination":["794-803"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12872259"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(8)"],"pubmed_abstract":["<h4>Objective</h4>The primary goal of this study was to determine how structural and functional parameters influence the vision-related quality of life (VRQoL) in patients suffering from geographic atrophy (GA) secondary to age-related macular degeneration.<h4>Design</h4>This study was designed as a prospective, noninterventional, natural-history study (Directional Spread in Geographic-Atrophy study, NCT02051998).<h4>Subjects</h4>The research involved 82 patients with bilateral GA.<h4>Methods</h4>The study examined parameters including GA location as assessed by the ETDRS grid, best-corrected visual acuity, low-luminance visual acuity (LLVA), reading acuity, and speed. These parameters were then correlated with VRQoL, which was gauged using the National Eye Institute Visual Function Questi"],"journal":["Ophthalmology. Retina"],"pubmed_title":["Association of Lesion Location and Functional Parameters with Vision-Related Quality of Life in Geographic Atrophy Secondary to Age-related Macular Degeneration."],"pmcid":["PMC12872259"],"funding_grant_id":["R01 EY034965","P30 EY014800","R01 EY033365"],"pubmed_authors":["Fleckenstein M","Moller PT","Schmitz-Valckenberg S","Broadbent E","Goerdt L","Czauderna J","Holz FG","Lindner M","Pfau M","Kunzel SH"],"additional_accession":[]},"is_claimable":false,"name":"Association of Lesion Location and Functional Parameters with Vision-Related Quality of Life in Geographic Atrophy Secondary to Age-related Macular Degeneration.","description":"<h4>Objective</h4>The primary goal of this study was to determine how structural and functional parameters influence the vision-related quality of life (VRQoL) in patients suffering from geographic atrophy (GA) secondary to age-related macular degeneration.<h4>Design</h4>This study was designed as a prospective, noninterventional, natural-history study (Directional Spread in Geographic-Atrophy study, NCT02051998).<h4>Subjects</h4>The research involved 82 patients with bilateral GA.<h4>Methods</h4>The study examined parameters including GA location as assessed by the ETDRS grid, best-corrected visual acuity, low-luminance visual acuity (LLVA), reading acuity, and speed. These parameters were then correlated with VRQoL, which was gauged using the National Eye Institute Visual Function Questi","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2026-07-05T03:11:02.261Z","creation":"2026-07-05T03:08:19.035Z"},"accession":"S-EPMC12872259","cross_references":{"pubmed":["38311207"],"doi":["10.1016/j.oret.2024.01.025"]}}