{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhao H"],"funding":["Science and Technology Planning Project of Chengguan District, Lanzhou City","Hongliu Outstanding Youth program 2023","Key Research and Development Program of Gannan Prefecture","National Natural Science Foundation of China"],"pagination":["409"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12896772"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(3)"],"pubmed_abstract":["Fructose dietary intake is one of the most common risk factors for hyperuricemia, which is a critical threat to human health, and the lack of an effective biological intervention method is the main problem in preventing hyperuricemia caused by fructose intake. <i>Lacticaseibacillus rhamnosus</i> Fmb14 (<i>L. rhamnosus</i> Fmb14) has a fructose-metabolizing ability to produce extracellular polysaccharides (EPSs), and the yield of EPSs reached 0.50 and 0.42 g/L after 48 h of fermentation in liquid media of glucose-MRS and fructose-MRS. Six pure polysaccharide components were obtained after purification. A hyperuricemic mouse model was subsequently established by feeding a 60% high-fructose diet with potassium oxyazinate for 8 weeks, and the results revealed that <i>L. rhamnosus</i> Fmb14 and"],"journal":["Foods (Basel, Switzerland)"],"pubmed_title":["Exopolysaccharides from &lt;i&gt;Lacticaseibacillus rhamnosus&lt;/i&gt; Fmb14 Ameliorate Fructose-Induced Hyperuricemia and Fatty Liver via Gut Modulation."],"pmcid":["PMC12896772"],"funding_grant_id":["grants 2024RCCX0022 to Song Li","grants 2025ZY1N007 to Song Li","grants 062402 to Zhao Hongyuan","grants 32072182 to Zhaoxin Lu"],"pubmed_authors":["Song L","Zhang Z","Lu Y","Lu Z","Tang C","Chen X","Zhao H"],"additional_accession":[]},"is_claimable":false,"name":"Exopolysaccharides from &lt;i&gt;Lacticaseibacillus rhamnosus&lt;/i&gt; Fmb14 Ameliorate Fructose-Induced Hyperuricemia and Fatty Liver via Gut Modulation.","description":"Fructose dietary intake is one of the most common risk factors for hyperuricemia, which is a critical threat to human health, and the lack of an effective biological intervention method is the main problem in preventing hyperuricemia caused by fructose intake. <i>Lacticaseibacillus rhamnosus</i> Fmb14 (<i>L. rhamnosus</i> Fmb14) has a fructose-metabolizing ability to produce extracellular polysaccharides (EPSs), and the yield of EPSs reached 0.50 and 0.42 g/L after 48 h of fermentation in liquid media of glucose-MRS and fructose-MRS. Six pure polysaccharide components were obtained after purification. A hyperuricemic mouse model was subsequently established by feeding a 60% high-fructose diet with potassium oxyazinate for 8 weeks, and the results revealed that <i>L. rhamnosus</i> Fmb14 and","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-07-07T03:14:35.953Z","creation":"2026-07-07T03:09:50.636Z"},"accession":"S-EPMC12896772","cross_references":{"pubmed":["41682997"],"doi":["10.3390/foods15030409"]}}