{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["18(3)"],"submitter":["Alfonso-Comos P"],"pubmed_abstract":["<b>Background</b>: Childhood cancer is the leading cause of natural death among children in high-income countries, despite treatment improvements. The Spanish Registry of Childhood Tumours (RETI-SEHOP) systematically records all cases treated within the network of SEHOP units. Using RETI-SEHOP data, we evaluated survival trends to assess progress in patient care, both overall and by tumour. <b>Methods</b>: A total of 20,534 childhood cancer cases (0-14 years) were recorded across the period 1999-2021. The 1-, 3-, and 5-year overall survival (OS) were estimated using the Kaplan-Meier method, applying the cohort approach for 1999-2018 and the period approach for 2019-2022. OS by age and sex was analysed in the recent 2009-2018 incidence cohort. Age-adjusted OS time trends were examined using"],"journal":["Cancers"],"pagination":["362"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12897301"],"repository":["biostudies-literature"],"pubmed_title":["Spanish Paediatric Haematology and Oncology Survival Results and Trends, 1999-2022."],"pmcid":["PMC12897301"],"pubmed_authors":["Canete A","Reti-Sehop Survival Working Group","Verdu-Amoros J","Fernandez Navarro JM","Briz-Redon A","Rives S","Alfonso-Comos P","Dapena Diaz JL"],"additional_accession":[]},"is_claimable":false,"name":"Spanish Paediatric Haematology and Oncology Survival Results and Trends, 1999-2022.","description":"<b>Background</b>: Childhood cancer is the leading cause of natural death among children in high-income countries, despite treatment improvements. The Spanish Registry of Childhood Tumours (RETI-SEHOP) systematically records all cases treated within the network of SEHOP units. Using RETI-SEHOP data, we evaluated survival trends to assess progress in patient care, both overall and by tumour. <b>Methods</b>: A total of 20,534 childhood cancer cases (0-14 years) were recorded across the period 1999-2021. The 1-, 3-, and 5-year overall survival (OS) were estimated using the Kaplan-Meier method, applying the cohort approach for 1999-2018 and the period approach for 2019-2022. OS by age and sex was analysed in the recent 2009-2018 incidence cohort. Age-adjusted OS time trends were examined using","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-07-08T03:15:30.505Z","creation":"2026-07-08T03:08:39.266Z"},"accession":"S-EPMC12897301","cross_references":{"pubmed":["41681835"],"doi":["10.3390/cancers18030362"]}}