biostudies-literatureElkins IBeef Cattle InstituteVeterinary Research Scholars ProgramFoundation for Food and Agriculture Research372https://www.ebi.ac.uk/biostudies/studies/S-EPMC12897432biostudies-literatureUnknown16(3)Cow efficiency is vitally important to beef sustainability, and computer simulation models may be useful tools to identify characteristics of the most efficient cow genotypes for a given production environment. The objective of this analysis was to determine whether the Beef Cattle Systems Model could replicate empirical research demonstrating a genotype-nutritional environment interaction for efficiency of feed conversion to calves weaned. Combinations of cow genotypes for lactation potential (8, 10, and 12 kg/d at peak milk) and growth potential (450, 505, and 650 kg mature weight) were simulated across four dry matter intake levels (58, 76, 93, and 111 g/kg BW^0.75). At lower dry matter intakes, cows had lesser body condition scores and weight and longer postpartum intervals, Animals : an open access journal from MDPIEvaluation of the Beef Cattle Systems Model to Replicate a Beef Cow Genotype × Nutritional Environment Interaction.PMC12897432N/AElkins ILarson RLLancaster PAThompson LfalseEvaluation of the Beef Cattle Systems Model to Replicate a Beef Cow Genotype × Nutritional Environment Interaction.Cow efficiency is vitally important to beef sustainability, and computer simulation models may be useful tools to identify characteristics of the most efficient cow genotypes for a given production environment. The objective of this analysis was to determine whether the Beef Cattle Systems Model could replicate empirical research demonstrating a genotype-nutritional environment interaction for efficiency of feed conversion to calves weaned. Combinations of cow genotypes for lactation potential (8, 10, and 12 kg/d at peak milk) and growth potential (450, 505, and 650 kg mature weight) were simulated across four dry matter intake levels (58, 76, 93, and 111 g/kg BW^0.75). At lower dry matter intakes, cows had lesser body condition scores and weight and longer postpartum intervals, 2026-01-01T00:00:00Z2026 Jan2026-07-09T10:24:29.998Z2026-07-09T10:19:45.319ZS-EPMC128974324168135410.3390/ani16030372