{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["27(3)"],"submitter":["Gangemi S"],"pubmed_abstract":["Sensitization to non-specific lipid transfer proteins (nsLTPs) is highly prevalent in Mediterranean countries. Pru p 3 from peach is a major allergen responsible for IgE-mediated food allergies. As a panallergen, Pru p 3 shows high sequence homology with nsLTPs from other Rosaceae fruits but also from botanically unrelated sources, including nuts and pollens, leading to extensive cross-reactivity complicating diagnosis and management. Given the worldwide prevalence of peanut and tree nut allergies, this study aimed to investigate sensitization patterns in Pru p 3-sensitized patients with tree nut allergy, using artificial intelligence (AI) to identify predictors of clinical reactivity and severity. Data from Pru p 3-sensitized patients with symptoms to peach and/or nuts were analyzed. Sens"],"journal":["International journal of molecular sciences"],"pagination":["1223"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12897624"],"repository":["biostudies-literature"],"pubmed_title":["The Role of Nut Sensitization in Pru p 3-Sensitized Patients: A XGBoost and Generalized Linear Model Application."],"pmcid":["PMC12897624"],"pubmed_authors":["Caristi G","Alessandrello C","Nuccio F","Minciullo PL","Gangemi S","Dimasi F","Morabito M"],"additional_accession":[]},"is_claimable":false,"name":"The Role of Nut Sensitization in Pru p 3-Sensitized Patients: A XGBoost and Generalized Linear Model Application.","description":"Sensitization to non-specific lipid transfer proteins (nsLTPs) is highly prevalent in Mediterranean countries. Pru p 3 from peach is a major allergen responsible for IgE-mediated food allergies. As a panallergen, Pru p 3 shows high sequence homology with nsLTPs from other Rosaceae fruits but also from botanically unrelated sources, including nuts and pollens, leading to extensive cross-reactivity complicating diagnosis and management. Given the worldwide prevalence of peanut and tree nut allergies, this study aimed to investigate sensitization patterns in Pru p 3-sensitized patients with tree nut allergy, using artificial intelligence (AI) to identify predictors of clinical reactivity and severity. Data from Pru p 3-sensitized patients with symptoms to peach and/or nuts were analyzed. Sens","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-07-07T03:10:47.173Z","creation":"2026-07-07T03:09:37.402Z"},"accession":"S-EPMC12897624","cross_references":{"pubmed":["41683649"],"doi":["10.3390/ijms27031223"]}}