{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sakuraoka R"],"funding":["Calbee, Inc."],"pagination":["456"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12898583"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["31(3)"],"pubmed_abstract":["Sweet potatoes (<i>Ipomoea batatas</i> (L.) Lam.) are known for their anti-inflammatory effects, which are attributed to their phytochemical content. Our previous study revealed that ethanol extracts of sweet potato storage roots (SP-EtOH-Ex) inhibit interleukin-6 (IL-6) production in RAW264.7 cells stimulated with lipopolysaccharide (LPS). However, the causative compounds responsible for the anti-inflammatory effect have not yet been identified. This study aims to identify the compounds responsible for the anti-inflammatory effect of SP-EtOH-Ex using liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS). The unknown compounds were measured using the auto MS/MS mode (data-dependent acquisition; DDA) of LC-Q-TOF-MS, and the resulting data were analyzed using MS-DIA"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Identification of Active Anti-Inflammatory Compounds in Sweet Potato Storage Roots Extracted with Ethanol via LC-Q-TOF-MS."],"pmcid":["PMC12898583"],"funding_grant_id":["No grant number"],"pubmed_authors":["Masutomi H","Ishihara K","Sakuraoka R"],"additional_accession":[]},"is_claimable":false,"name":"Identification of Active Anti-Inflammatory Compounds in Sweet Potato Storage Roots Extracted with Ethanol via LC-Q-TOF-MS.","description":"Sweet potatoes (<i>Ipomoea batatas</i> (L.) Lam.) are known for their anti-inflammatory effects, which are attributed to their phytochemical content. Our previous study revealed that ethanol extracts of sweet potato storage roots (SP-EtOH-Ex) inhibit interleukin-6 (IL-6) production in RAW264.7 cells stimulated with lipopolysaccharide (LPS). However, the causative compounds responsible for the anti-inflammatory effect have not yet been identified. This study aims to identify the compounds responsible for the anti-inflammatory effect of SP-EtOH-Ex using liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS). The unknown compounds were measured using the auto MS/MS mode (data-dependent acquisition; DDA) of LC-Q-TOF-MS, and the resulting data were analyzed using MS-DIA","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-07-07T03:15:04.206Z","creation":"2026-07-07T03:09:51.918Z"},"accession":"S-EPMC12898583","cross_references":{"pubmed":["41683433"],"doi":["10.3390/molecules31030456"]}}