{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Boyadzhieva SS"],"funding":["European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie"],"pagination":["525"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12899463"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["31(3)"],"pubmed_abstract":["A hybrid two-route strategy for converting <i>Cornus mas</i> L. stones into bioactive and other high-value compounds was developed and thoroughly evaluated. In Route 1, microwave-assisted extraction (MAE) is applied directly to the stones biomass following an experimental design created with Design Expert 11. Route 2 involves Soxhlet <i>n</i>-hexane extraction of the raw biomass, followed by MAE of the resulting defatted residue. The efficiency of the two routes was evaluated by comparing total polyphenol, flavonoid, and saponin content (TPC, TFC, TSC) and antioxidant activity (AA) of all obtained extracts, the fatty acid composition of MAE (route 1) and Soxhlet <i>n</i>-hexane extracts, and the metabolite composition of MAE extracts recovered in Route 1 and Route 2. The series of analyses"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Boosting the Sustainable Transformation of &lt;i&gt;Cornus mas&lt;/i&gt; L. Stones Using a Hybrid Strategy Involving Microwave-Assisted Extraction."],"pmcid":["PMC12899463"],"funding_grant_id":["778168"],"pubmed_authors":["Staleva P","Coelho JAP","Taneva S","Stateva RP","Boyadzhieva SS","Kamenova-Nacheva M","Tsvetanova FV"],"additional_accession":[]},"is_claimable":false,"name":"Boosting the Sustainable Transformation of &lt;i&gt;Cornus mas&lt;/i&gt; L. Stones Using a Hybrid Strategy Involving Microwave-Assisted Extraction.","description":"A hybrid two-route strategy for converting <i>Cornus mas</i> L. stones into bioactive and other high-value compounds was developed and thoroughly evaluated. In Route 1, microwave-assisted extraction (MAE) is applied directly to the stones biomass following an experimental design created with Design Expert 11. Route 2 involves Soxhlet <i>n</i>-hexane extraction of the raw biomass, followed by MAE of the resulting defatted residue. The efficiency of the two routes was evaluated by comparing total polyphenol, flavonoid, and saponin content (TPC, TFC, TSC) and antioxidant activity (AA) of all obtained extracts, the fatty acid composition of MAE (route 1) and Soxhlet <i>n</i>-hexane extracts, and the metabolite composition of MAE extracts recovered in Route 1 and Route 2. The series of analyses","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-08T03:09:31.906Z","creation":"2026-07-08T03:07:32.969Z"},"accession":"S-EPMC12899463","cross_references":{"pubmed":["41683502"],"doi":["10.3390/molecules31030525"]}}