{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["26(3)"],"submitter":["Qin N"],"pubmed_abstract":["In this work, highly water-soluble silk fibroin (SF) is first prepared by recrystallizing degummed silkworm cocoon fibers in concentrated CaCl<sub>2</sub> solution (replacing the conventional Ajisawa's reagent), and then used as both stabilizing and reducing agents to synthesize copper nanoclusters (Cu@SF NCs) at pH = 11. Due to the existence of unreacted Cu<sup>2+</sup> ions, the resulting SF-templated Cu NCs form slight aggregates, yielding a purple-colored solution with blue fluorescence. Interestingly, upon adding the pesticide 2,4-dichlorophenoxyacetic acid (2,4-D), the Cu NCs aggregates disassemble and the fluorescence is significantly enhanced, creating a \"fluorescence-on\" sensor for 2,4-D with a detection limit of 0.65 μM. In contrast, the pollutant p-nitrophenol (p-NP) quenches th"],"journal":["Sensors (Basel, Switzerland)"],"pagination":["784"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12899482"],"repository":["biostudies-literature"],"pubmed_title":["Silk Fibroin-Templated Copper Nanoclusters: Responsive Fluorescent Probes Exhibiting 2,4-Dichlorophenoxyacetic Acid-Enhanced Emission and p-Nitrophenol-Induced Quenching."],"pmcid":["PMC12899482"],"pubmed_authors":["Tao J","Han MY","Qin N","Wang Q","Guan G"],"additional_accession":[]},"is_claimable":false,"name":"Silk Fibroin-Templated Copper Nanoclusters: Responsive Fluorescent Probes Exhibiting 2,4-Dichlorophenoxyacetic Acid-Enhanced Emission and p-Nitrophenol-Induced Quenching.","description":"In this work, highly water-soluble silk fibroin (SF) is first prepared by recrystallizing degummed silkworm cocoon fibers in concentrated CaCl<sub>2</sub> solution (replacing the conventional Ajisawa's reagent), and then used as both stabilizing and reducing agents to synthesize copper nanoclusters (Cu@SF NCs) at pH = 11. Due to the existence of unreacted Cu<sup>2+</sup> ions, the resulting SF-templated Cu NCs form slight aggregates, yielding a purple-colored solution with blue fluorescence. Interestingly, upon adding the pesticide 2,4-dichlorophenoxyacetic acid (2,4-D), the Cu NCs aggregates disassemble and the fluorescence is significantly enhanced, creating a \"fluorescence-on\" sensor for 2,4-D with a detection limit of 0.65 μM. In contrast, the pollutant p-nitrophenol (p-NP) quenches th","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-07-08T03:11:45.243Z","creation":"2026-07-08T03:08:38.303Z"},"accession":"S-EPMC12899482","cross_references":{"pubmed":["41682300"],"doi":["10.3390/s26030784"]}}