{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["18"],"submitter":["Kao YL"],"pubmed_abstract":["<h4>Background</h4>Contralateral recurrence of upper-tract urothelial carcinoma (UTUC) presents a clinical challenge, with limited evidence regarding optimal surgical management.<h4>Objective</h4>To compare oncological outcomes among patients with contralateral UTUC recurrence managed by second nephroureterectomy (NUR) or nephron-sparing surgery (NSS), relative to those undergoing primary NUR.<h4>Design</h4>A multicentre retrospective cohort study.<h4>Methods</h4>In this multicentre retrospective cohort, 3159 patients diagnosed with UTUC between 2018 and 2024 in the Taiwanese UTUC Registry were analysed. Patients undergoing curative-intent surgery were grouped as follows: unilateral UTUC treated with primary NUR; contralateral recurrence treated with a second NUR; and contralateral recurre"],"journal":["Therapeutic advances in urology"],"pagination":["17562872261419593"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12901921"],"repository":["biostudies-literature"],"pubmed_title":["Contralateral recurrent upper-tract urothelial carcinoma after curative surgery: a multicentre retrospective cohort study."],"pmcid":["PMC12901921"],"pubmed_authors":["Tsai CY","Chen IA","Ou CH","Wu HC","Huang CY","Chang CH","Wu WJ","Li CC","Tsai YC","Cheng PY","Kao YL","Yu CC"],"additional_accession":[]},"is_claimable":false,"name":"Contralateral recurrent upper-tract urothelial carcinoma after curative surgery: a multicentre retrospective cohort study.","description":"<h4>Background</h4>Contralateral recurrence of upper-tract urothelial carcinoma (UTUC) presents a clinical challenge, with limited evidence regarding optimal surgical management.<h4>Objective</h4>To compare oncological outcomes among patients with contralateral UTUC recurrence managed by second nephroureterectomy (NUR) or nephron-sparing surgery (NSS), relative to those undergoing primary NUR.<h4>Design</h4>A multicentre retrospective cohort study.<h4>Methods</h4>In this multicentre retrospective cohort, 3159 patients diagnosed with UTUC between 2018 and 2024 in the Taiwanese UTUC Registry were analysed. Patients undergoing curative-intent surgery were grouped as follows: unilateral UTUC treated with primary NUR; contralateral recurrence treated with a second NUR; and contralateral recurre","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan-Dec","modification":"2026-07-15T22:02:38.969Z","creation":"2026-07-09T13:09:37.333Z"},"accession":"S-EPMC12901921","cross_references":{"pubmed":["41694265"],"doi":["10.1177/17562872261419593"]}}