{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(5)"],"submitter":["Li L"],"pubmed_abstract":["The development of liquid embolic agents has significantly advanced the field of transcatheter arterial embolization (TAE). Conventional solid embolic agents, such as gelatin sponges or poly-(vinyl alcohol) (PVA), are limited by their lack of intrinsic radiopacity and reliance on lipiodol, necessitating a cumbersome two-step embolization process. Consequently, a critical need exists for embolic materials that combine intrinsic imaging functionality with enhanced biocompatibility to advance clinical outcomes. We have developed a novel liquid embolic material based on poly-(<i>N</i>-isopropylacrylamide)-<i>co</i>-acrylic acid nanogels (PNAs). Mixing PNAs with lipiodol using a medical three-way stopcock yields a thermosensitive lipiodol-based gel emulsion (TLGE). This material exhibits excell"],"journal":["ACS omega"],"pagination":["7451-7463"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12902837"],"repository":["biostudies-literature"],"pubmed_title":["A Radiopaque and Thermoresponsive Nanogel-Based Pickering Emulsion for Permanent Arterial Embolization."],"pmcid":["PMC12902837"],"pubmed_authors":["Chen N","Xing J","Cao Y","Liu A","Zhang L","Cheng G","Li L","Yu H"],"additional_accession":[]},"is_claimable":false,"name":"A Radiopaque and Thermoresponsive Nanogel-Based Pickering Emulsion for Permanent Arterial Embolization.","description":"The development of liquid embolic agents has significantly advanced the field of transcatheter arterial embolization (TAE). Conventional solid embolic agents, such as gelatin sponges or poly-(vinyl alcohol) (PVA), are limited by their lack of intrinsic radiopacity and reliance on lipiodol, necessitating a cumbersome two-step embolization process. Consequently, a critical need exists for embolic materials that combine intrinsic imaging functionality with enhanced biocompatibility to advance clinical outcomes. We have developed a novel liquid embolic material based on poly-(<i>N</i>-isopropylacrylamide)-<i>co</i>-acrylic acid nanogels (PNAs). Mixing PNAs with lipiodol using a medical three-way stopcock yields a thermosensitive lipiodol-based gel emulsion (TLGE). This material exhibits excell","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-15T15:36:12.632Z","creation":"2026-07-06T03:11:01.206Z"},"accession":"S-EPMC12902837","cross_references":{"pubmed":["41696235"],"doi":["10.1021/acsomega.5c08513"]}}