biostudies-literatureUnknown11(5)Ghaffari SAs part of the CODA project, which is laying the foundation for a novel sustainable soda ash (Na₂CO₃) production strategy, this study provides essential parameters and insights for the design, optimization, and scale-up of the required crystallization processes. It investigates the crystal growth kinetics of Na₂CO₃·10H₂O and Na₂CO₃·1H₂O within the Na₂CO₃-NaOH-H₂O system using cooling and vacuum evaporative crystallization, respectively. Experimental studies were conducted utilizing a shortcut method based on seeded batch experiments in a 3 L-scale. The growth rate of Na₂CO₃·10H₂O was studied over a temperature range of 17-6 °C, while Na<sACS omega7741-7755https://www.ebi.ac.uk/biostudies/studies/S-EPMC12903160biostudies-literatureCrystal Growth Kinetics of Na &lt;sub&gt;&lt;b&gt;2&lt;/b&gt;&lt;/sub&gt; CO &lt;sub&gt;&lt;b&gt;3&lt;/b&gt;&lt;/sub&gt; Hydrate Phases in the Na &lt;sub&gt;&lt;b&gt;2&lt;/b&gt;&lt;/sub&gt; CO &lt;sub&gt;&lt;b&gt;3&lt;/b&gt;&lt;/sub&gt; -NaOH-H &lt;sub&gt;&lt;b&gt;2&lt;/b&gt;&lt;/sub&gt; O System for Sustainable Soda Ash Production.PMC12903160Lorenz HSchulze PGansch JGhaffari SfalseCrystal Growth Kinetics of Na &lt;sub&gt;&lt;b&gt;2&lt;/b&gt;&lt;/sub&gt; CO &lt;sub&gt;&lt;b&gt;3&lt;/b&gt;&lt;/sub&gt; Hydrate Phases in the Na &lt;sub&gt;&lt;b&gt;2&lt;/b&gt;&lt;/sub&gt; CO &lt;sub&gt;&lt;b&gt;3&lt;/b&gt;&lt;/sub&gt; -NaOH-H &lt;sub&gt;&lt;b&gt;2&lt;/b&gt;&lt;/sub&gt; O System for Sustainable Soda Ash Production.As part of the CODA project, which is laying the foundation for a novel sustainable soda ash (Na₂CO₃) production strategy, this study provides essential parameters and insights for the design, optimization, and scale-up of the required crystallization processes. It investigates the crystal growth kinetics of Na₂CO₃·10H₂O and Na₂CO₃·1H₂O within the Na₂CO₃-NaOH-H₂O system using cooling and vacuum evaporative crystallization, respectively. Experimental studies were conducted utilizing a shortcut method based on seeded batch experiments in a 3 L-scale. The growth rate of Na₂CO₃·10H₂O was studied over a temperature range of 17-6 °C, while Na<s2026-01-01T00:00:00Z2026 Feb2026-07-15T17:27:51.945Z2026-07-07T03:08:33.433ZS-EPMC129031604169620010.1021/acsomega.5c09440