{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li M"],"funding":["National Natural Science Foundation of China","Key R&D Program of Shandong Province","the National Natural Science Foundation of China"],"pagination":["e70225"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12904607"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(2)"],"pubmed_abstract":["Wheat (Triticum aestivum) is an important staple food crop worldwide, playing a fundamental role in global food security. Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a highly destructive disease affecting this crop. The Elongator complex is known to be a key regulator of plant responses to stress; however, little is known about the function of its subunit 2, encoded by the TaELP2 gene, in the wheat-Pst interaction. In this study, we investigated the role of TaELP2 in the susceptibility of wheat to Pst. We found that the transient silencing of TaELP2 using a virus-induced gene silencing (VIGS) system markedly increased wheat resistance to the pathogen, whereas its overexpression exerted the opposite effect. Subsequently, yeast two-hybrid (Y2H), luciferase comp"],"journal":["Molecular plant pathology"],"pubmed_title":["TaELP2 Interacts With TaDCL1 and Negatively Regulates Wheat Resistance Against Stripe Rust."],"pmcid":["PMC12904607"],"funding_grant_id":["U24 A20406","32293243","2023LZGC002","32572846"],"pubmed_authors":["Zhang Z","Zhang X","Chen Y","Guo S","Kang Z","Wang J","Li M"],"additional_accession":[]},"is_claimable":false,"name":"TaELP2 Interacts With TaDCL1 and Negatively Regulates Wheat Resistance Against Stripe Rust.","description":"Wheat (Triticum aestivum) is an important staple food crop worldwide, playing a fundamental role in global food security. Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a highly destructive disease affecting this crop. The Elongator complex is known to be a key regulator of plant responses to stress; however, little is known about the function of its subunit 2, encoded by the TaELP2 gene, in the wheat-Pst interaction. In this study, we investigated the role of TaELP2 in the susceptibility of wheat to Pst. We found that the transient silencing of TaELP2 using a virus-induced gene silencing (VIGS) system markedly increased wheat resistance to the pathogen, whereas its overexpression exerted the opposite effect. Subsequently, yeast two-hybrid (Y2H), luciferase comp","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-15T18:01:00.067Z","creation":"2026-07-08T03:08:01.536Z"},"accession":"S-EPMC12904607","cross_references":{"pubmed":["41687022"],"doi":["10.1111/mpp.70225"]}}