{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["67"],"submitter":["Marincek F"],"pubmed_abstract":["<h4>Background</h4><i>Streptococcus pneumoniae</i> (the pneumococcus) is one of the main causes of childhood mortality. Understanding pneumococcal serotype and lineage distribution in children is important for vaccine decision-making. We undertook a secondary analysis of nasopharyngeal swabs collected from unvaccinated children as part of pneumococcal vaccine studies to provide a comprehensive picture of pneumococcal carriage epidemiology in Vietnamese children during the first 60 months of life.<h4>Methods</h4>We analysed 4375 nasopharyngeal swabs from unvaccinated children to assess overall and vaccine-type pneumococcal carriage at 6, 12, 18, 24, and 60 months of age. For the latter three age groups, serotype distribution and genetic lineages (Global Pneumococcal Sequence Cluster, GPSCs)"],"journal":["The Lancet regional health. Western Pacific"],"pagination":["101805"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12906029"],"repository":["biostudies-literature"],"pubmed_title":["&lt;i&gt;Streptococcus pneumoniae&lt;/i&gt; nasopharyngeal carriage in Vietnamese children during the first five years of life: a post hoc analysis."],"pmcid":["PMC12906029"],"pubmed_authors":["Tran HP","Mulholland K","Smith-Vaughan H","Tran HN","Manna S","Satzke C","Loc Thuy HN","Tran PL","Hinds J","Wee-Hee A","Tuong Le VT","Spry L","Nguyen C","Nguyen TV","Doan UY","Trang Dai VT","Bright K","Temple B","Beissbarth J","Van Phan T","Marincek F","Pell C","Ortika B"],"additional_accession":[]},"is_claimable":false,"name":"&lt;i&gt;Streptococcus pneumoniae&lt;/i&gt; nasopharyngeal carriage in Vietnamese children during the first five years of life: a post hoc analysis.","description":"<h4>Background</h4><i>Streptococcus pneumoniae</i> (the pneumococcus) is one of the main causes of childhood mortality. Understanding pneumococcal serotype and lineage distribution in children is important for vaccine decision-making. We undertook a secondary analysis of nasopharyngeal swabs collected from unvaccinated children as part of pneumococcal vaccine studies to provide a comprehensive picture of pneumococcal carriage epidemiology in Vietnamese children during the first 60 months of life.<h4>Methods</h4>We analysed 4375 nasopharyngeal swabs from unvaccinated children to assess overall and vaccine-type pneumococcal carriage at 6, 12, 18, 24, and 60 months of age. For the latter three age groups, serotype distribution and genetic lineages (Global Pneumococcal Sequence Cluster, GPSCs)","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-15T16:31:47.376Z","creation":"2026-07-07T03:08:33.577Z"},"accession":"S-EPMC12906029","cross_references":{"pubmed":["41695238"],"doi":["10.1016/j.lanwpc.2026.101805"]}}