{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["67"],"submitter":["Zou Z"],"pubmed_abstract":["<h4>Background</h4>Hepatitis C virus (HCV) remains a global health concern, with cascade gaps hindering elimination. We aim to assess and compare HCV care cascades in four key populations: people living with HIV (PLHIV), people who inject drugs (PWID), men who have sex with men (MSM), and incarcerated individuals.<h4>Methods</h4>We conducted a systematic review and meta-analysis of observational studies (Jan 2019-Sept 2025) reporting ≥1 care cascade stage, including screening, confirmatory testing, linkage to care, treatment uptake and completion, and cure, among key populations (PROSPERO CRD42024577740). Four databases were searched. Pooled stage-specific proportions were estimated using random-effects meta-analysis, stratified by population and region.<h4>Findings</h4>We included 219 stu"],"journal":["The Lancet regional health. Western Pacific"],"pagination":["101803"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12906211"],"repository":["biostudies-literature"],"pubmed_title":["Progressing towards global hepatitis C elimination: a systematic review and meta-analysis of care cascades in key populations."],"pmcid":["PMC12906211"],"pubmed_authors":["Zou Z","Su S","Hu Y","Wang Q","Zhang Y","Cao Y","Zhang L"],"additional_accession":[]},"is_claimable":false,"name":"Progressing towards global hepatitis C elimination: a systematic review and meta-analysis of care cascades in key populations.","description":"<h4>Background</h4>Hepatitis C virus (HCV) remains a global health concern, with cascade gaps hindering elimination. We aim to assess and compare HCV care cascades in four key populations: people living with HIV (PLHIV), people who inject drugs (PWID), men who have sex with men (MSM), and incarcerated individuals.<h4>Methods</h4>We conducted a systematic review and meta-analysis of observational studies (Jan 2019-Sept 2025) reporting ≥1 care cascade stage, including screening, confirmatory testing, linkage to care, treatment uptake and completion, and cure, among key populations (PROSPERO CRD42024577740). Four databases were searched. Pooled stage-specific proportions were estimated using random-effects meta-analysis, stratified by population and region.<h4>Findings</h4>We included 219 stu","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-15T21:27:45.636Z","creation":"2026-07-09T10:14:22.763Z"},"accession":"S-EPMC12906211","cross_references":{"pubmed":["41695236"],"doi":["10.1016/j.lanwpc.2026.101803"]}}