{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["264(1)"],"submitter":["Ventura-Abreu N"],"funding":["Fundació Institució dels Centres de Recerca de Catalunya"],"pubmed_abstract":["Purpose
To characterize bleb morphology and conjunctival features after XEN45 Gel Stent surgery (XGS) using slit-lamp bleb grading, anterior segment optical coherence tomography (AS-OCT), in vivo confocal microscopy (IVCM), and impression cytology analysis (ICA), in both success and failure cases.Methods
Twenty-four eyes (24 patients) underwent XGS, with 20 included in the final analysis. In addition to a full ophthalmic exam, blebs were evaluated using Moorfield's Bleb Grading System (BGS), AS-OCT, IVCM, and ICA. AS-OCT metrics included bleb-wall and subepithelial cyst-like structure area and density (BECSA/BECSD, BSCSA/BSCSD), bleb height (BH), bleb thickness (BT), and epithelial thickness (BET). IVCM parameters included stromal meshwork reflectivity (SMR), goblet cell de"],"journal":["Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie"],"pagination":["207-218"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12906558"],"repository":["biostudies-literature"],"pubmed_title":["Longitudinal analysis of XEN45 gel stent bleb morphology using bleb grading scales, anterior segment-OCT, in vivo confocal microscopy, and impression cytology."],"pmcid":["PMC12906558"],"pubmed_authors":["Molins B","Ventura-Abreu N","Porto S","Pazos M","Guerra-Meniconi J","Labay-Tejado S","Muniesa MJ","Milla E"],"additional_accession":[]},"is_claimable":false,"name":"Longitudinal analysis of XEN45 gel stent bleb morphology using bleb grading scales, anterior segment-OCT, in vivo confocal microscopy, and impression cytology.","description":"Purpose
To characterize bleb morphology and conjunctival features after XEN45 Gel Stent surgery (XGS) using slit-lamp bleb grading, anterior segment optical coherence tomography (AS-OCT), in vivo confocal microscopy (IVCM), and impression cytology analysis (ICA), in both success and failure cases.Methods
Twenty-four eyes (24 patients) underwent XGS, with 20 included in the final analysis. In addition to a full ophthalmic exam, blebs were evaluated using Moorfield's Bleb Grading System (BGS), AS-OCT, IVCM, and ICA. AS-OCT metrics included bleb-wall and subepithelial cyst-like structure area and density (BECSA/BECSD, BSCSA/BSCSD), bleb height (BH), bleb thickness (BT), and epithelial thickness (BET). IVCM parameters included stromal meshwork reflectivity (SMR), goblet cell de","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-07-15T21:23:04.55Z","creation":"2026-07-09T10:13:37.902Z"},"accession":"S-EPMC12906558","cross_references":{"pubmed":["41042361"],"doi":["10.1007/s00417-025-06952-0"]}}