biostudies-literatureUnknown17Ye L<h4>Background</h4>Executive function deficits are common among patients with Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Executive function refers to higher-order cognitive processes thought to involve fronto-striatal circuits. Some patients with executive deficits may be unable to recognize or report them, a condition we refer to as executive anosognosia.<h4>Objective</h4>To conduct a comparative analysis of executive anosognosia in patients diagnosed with PSP and PD.<h4>Methods</h4>We compared an objective neuropsychological assessment (ONA) of composite executive function (ONA-CEF), which includes semantic and phonemic verbal fluency, as well as two sub-scores from the Wisconsin Card Sorting Test, with patient- and informant-reported rating scales. We used the DyFrontiers in neurology1744979https://www.ebi.ac.uk/biostudies/studies/S-EPMC12907162biostudies-literatureExecutive anosognosia in progressive supranuclear palsy versus Parkinson's disease.PMC12907162Niesmann CYe LHoglinger GUSeidler LWilkens IChemodanow DRespondek GKopp BKlietz MfalseExecutive anosognosia in progressive supranuclear palsy versus Parkinson's disease.<h4>Background</h4>Executive function deficits are common among patients with Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Executive function refers to higher-order cognitive processes thought to involve fronto-striatal circuits. Some patients with executive deficits may be unable to recognize or report them, a condition we refer to as executive anosognosia.<h4>Objective</h4>To conduct a comparative analysis of executive anosognosia in patients diagnosed with PSP and PD.<h4>Methods</h4>We compared an objective neuropsychological assessment (ONA) of composite executive function (ONA-CEF), which includes semantic and phonemic verbal fluency, as well as two sub-scores from the Wisconsin Card Sorting Test, with patient- and informant-reported rating scales. We used the Dy2026-01-01T00:00:00Z20262026-07-16T05:12:02.933Z2026-07-09T10:36:52.989ZS-EPMC129071624170489010.3389/fneur.2026.1744979