{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["27(2)"],"submitter":["Lin CY"],"pubmed_abstract":["<h4>Background</h4>Conventional cone-beam computed tomography (CBCT) systems are limited by suboptimal image quality, inaccurate Hounsfield unit (HU) calibration, and reduced reliability for dose calculation. HyperSight CBCT on the Halcyon platform offers improved HU accuracy, expanded field-of-view (FOV), and enhanced image quality.<h4>Purpose</h4>This study aimed to assess the dosimetric accuracy of treatment planning using HyperSight CBCT through phantom-based dose verification.<h4>Methods</h4>This study included three institutions equipped with the HyperSight imaging system on the Halcyon platform, with all procedures performed after acceptance testing and calibration. Each institution generated HU-to-density calibration curves using computed tomography (CT) scanners and standardized p"],"journal":["Journal of applied clinical medical physics"],"pagination":["e70512"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12909596"],"repository":["biostudies-literature"],"pubmed_title":["Multi-institutional validation of hypersight CBCT-based dose calculation on O-ring linacs."],"pmcid":["PMC12909596"],"pubmed_authors":["Hsieh YW","Chang CC","Chao TY","Yeh CY","Chao HP","Liu FH","Lin YW","Hsu SM","Pan CP","Chen YL","Hu YH","Lin CY"],"additional_accession":[]},"is_claimable":false,"name":"Multi-institutional validation of hypersight CBCT-based dose calculation on O-ring linacs.","description":"<h4>Background</h4>Conventional cone-beam computed tomography (CBCT) systems are limited by suboptimal image quality, inaccurate Hounsfield unit (HU) calibration, and reduced reliability for dose calculation. HyperSight CBCT on the Halcyon platform offers improved HU accuracy, expanded field-of-view (FOV), and enhanced image quality.<h4>Purpose</h4>This study aimed to assess the dosimetric accuracy of treatment planning using HyperSight CBCT through phantom-based dose verification.<h4>Methods</h4>This study included three institutions equipped with the HyperSight imaging system on the Halcyon platform, with all procedures performed after acceptance testing and calibration. Each institution generated HU-to-density calibration curves using computed tomography (CT) scanners and standardized p","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-16T00:47:16.83Z","creation":"2026-07-09T10:26:27.588Z"},"accession":"S-EPMC12909596","cross_references":{"pubmed":["41699857"],"doi":["10.1002/acm2.70512"]}}