{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["27(1)"],"submitter":["Ershov A"],"pubmed_abstract":["<h4>Background</h4>High-throughput sequencing technologies generate massive amounts of FASTQ data comprising nucleotide sequences, quality scores, and read identifiers, necessitating efficient compression to alleviate storage and transmission burdens. Compared to general-purpose compressors, specialized FASTQ compressors achieve higher compression performance by exploiting the inherent redundancy in FASTQ files. However, existing FASTQ-specialized compressors often suffer from limited data applicability and tend to over-optimize either compression ratio or compression speed at the expense of the other.<h4>Results</h4>We present zDUR, a reference-free FASTQ compressor designed for efficient and scalable handling of next-generation sequencing data across diverse platforms and sequencing data"],"journal":["BMC bioinformatics"],"pagination":["46"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12911337"],"repository":["biostudies-literature"],"pubmed_title":["zDUR: reference-free FASTQ compressor with high compression ratio and speed."],"pmcid":["PMC12911337"],"pubmed_authors":["Mozheiko E","Fu Q","Ding R","Kozlov I","Ershov A","Zhou Y","Ni M","Hou Y","Fadeeva E"],"additional_accession":[]},"is_claimable":false,"name":"zDUR: reference-free FASTQ compressor with high compression ratio and speed.","description":"<h4>Background</h4>High-throughput sequencing technologies generate massive amounts of FASTQ data comprising nucleotide sequences, quality scores, and read identifiers, necessitating efficient compression to alleviate storage and transmission burdens. Compared to general-purpose compressors, specialized FASTQ compressors achieve higher compression performance by exploiting the inherent redundancy in FASTQ files. However, existing FASTQ-specialized compressors often suffer from limited data applicability and tend to over-optimize either compression ratio or compression speed at the expense of the other.<h4>Results</h4>We present zDUR, a reference-free FASTQ compressor designed for efficient and scalable handling of next-generation sequencing data across diverse platforms and sequencing data","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-07-16T00:40:16.576Z","creation":"2026-07-09T10:25:51.057Z"},"accession":"S-EPMC12911337","cross_references":{"pubmed":["41578172"],"doi":["10.1186/s12859-025-06364-1"]}}