{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Leite-Barbosa O"],"funding":["Conselho Nacional de Desenvolvimento Científico e Tecnológico","Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ)","National Council for Scientific and Technological Development (CNPq)"],"pagination":["e70048"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12911472"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["40(10)"],"pubmed_abstract":["<h4>Rationale</h4>The migration of phthalate plasticizers from high-volume polymers, such as poly(vinyl chloride) (PVC), raises significant toxicological concerns, particularly when materials are subjected to aging and environmental stress. As traditional monitoring techniques rely on time-consuming solvent extraction and chromatographic methods that are often expensive and lack the throughput required for large-scale safety screening, this study intends to present a rapid screening method using direct analysis in real time coupled to high-resolution mass spectrometry (DART-HRMS) to monitor plasticizer migration in PVC films subjected to accelerated UV aging. Operational parameters, such as ionization gas temperature and grid voltage, were systematically optimized to balance desorption eff"],"journal":["Rapid communications in mass spectrometry : RCM"],"pubmed_title":["Rapid Detection of Plasticizer Migration From UV-Aged PVC Films by DART-HRMS."],"pmcid":["PMC12911472"],"funding_grant_id":["310782/2022-8","E-26/200.512/2023","E-26/211.315/2021","310782/2022‐8"],"pubmed_authors":["Padilha MC","Veiga-Junior VF","de Oliveira MG","Leite-Barbosa O","de Oliveira MFL"],"additional_accession":[]},"is_claimable":false,"name":"Rapid Detection of Plasticizer Migration From UV-Aged PVC Films by DART-HRMS.","description":"<h4>Rationale</h4>The migration of phthalate plasticizers from high-volume polymers, such as poly(vinyl chloride) (PVC), raises significant toxicological concerns, particularly when materials are subjected to aging and environmental stress. As traditional monitoring techniques rely on time-consuming solvent extraction and chromatographic methods that are often expensive and lack the throughput required for large-scale safety screening, this study intends to present a rapid screening method using direct analysis in real time coupled to high-resolution mass spectrometry (DART-HRMS) to monitor plasticizer migration in PVC films subjected to accelerated UV aging. Operational parameters, such as ionization gas temperature and grid voltage, were systematically optimized to balance desorption eff","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 May","modification":"2026-07-16T00:35:24.089Z","creation":"2026-07-09T10:25:54.024Z"},"accession":"S-EPMC12911472","cross_references":{"pubmed":["41700866"],"doi":["10.1002/rcm.70048"]}}