{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Xu S"],"funding":["NEI NIH HHS","National Eye Institute","NIA NIH HHS","National Institute on Aging"],"pubmed_abstract":["ObjectivesSensory loss is associated with increased dementia risk, yet the underlying mechanisms remain unclear. This longitudinal study examined the association between self-reported sensory difficulty (vision, hearing, dual), social and physical activity, and dementia risk among older U.S. adults.MethodsData were drawn from the 2015-2020 National Health and Aging Trends Study (<i>N</i> = 6,295). Discrete-time survival mediation models with a structural equation modeling-based approach were estimated to examine the associations.ResultsDementia incidence was highest among those with dual sensory difficulty (21.8%), followed by visual (18.8%) and hearing (13.2%) difficulties. Visual difficulty and dual sensory difficulty were associated with decreased social activities and incident dementia"],"journal":["Journal of aging and health"],"pagination":["8982643251364364"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12911503"],"repository":["biostudies-literature"],"pubmed_title":["Sensory Difficulty, Social and Physical Activity, and Dementia Risk Among Older Adults."],"pmcid":["PMC12911503"],"funding_grant_id":["R61 AG089063","R01 EY034479","R01EY034479","R61AG089063"],"pubmed_authors":["Song Q","Ehrlich JR","Xu S","Burr JA"],"additional_accession":[]},"is_claimable":false,"name":"Sensory Difficulty, Social and Physical Activity, and Dementia Risk Among Older Adults.","description":"ObjectivesSensory loss is associated with increased dementia risk, yet the underlying mechanisms remain unclear. This longitudinal study examined the association between self-reported sensory difficulty (vision, hearing, dual), social and physical activity, and dementia risk among older U.S. adults.MethodsData were drawn from the 2015-2020 National Health and Aging Trends Study (<i>N</i> = 6,295). Discrete-time survival mediation models with a structural equation modeling-based approach were estimated to examine the associations.ResultsDementia incidence was highest among those with dual sensory difficulty (21.8%), followed by visual (18.8%) and hearing (13.2%) difficulties. Visual difficulty and dual sensory difficulty were associated with decreased social activities and incident dementia","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-07-16T00:41:05.772Z","creation":"2026-07-09T10:26:04.348Z"},"accession":"S-EPMC12911503","cross_references":{"pubmed":["40747808"],"doi":["10.1177/08982643251364364"]}}